Development of the sympatho-vagal balance in the cardiovascular system in zebrafish (Danio rerio) characterized by power spectrum and classical signal analysis

The Journal of Experimental Biology
Thorsten SchwerteBernd Pelster

Abstract

The development of sympatho-vagal control of cardiac activity was analyzed in zebrafish (Danio rerio) larvae from 2 to 15 days post fertilization (d.p.f.) by pharmacological studies as well as by assessing short term heart rate variability. Changes in heart rate in response to cholinergic and adrenergic receptor stimulation or inhibition were investigated using in situ preparations and digital video-microscopic techniques. The data revealed that the heart responded to adrenergic stimulation starting at 4 d.p.f. and to cholinergic stimulation starting at 5 d.p.f. Atropine application resulted in an increase in heart rate beyond 12 d.p.f., while the inhibitory effect of cholinergic stimulation ceased at this time of development. Adrenergic inhibition (propranolol) reduced heart rate for the first time at 5 d.p.f., but the reduction was only very small (3.8%). Between 5 and 12 d.p.f. propranolol application always resulted in a minor reduction in heart rate, but because the effect was so small it was not always significant. Because the presence of an adrenergic or cholinergic tone may influence the stability of heart rate, we analyzed short-term heart rate variability (HRV). The frequency band width of heart rate variability revea...Continue Reading

References

Jan 1, 1992·The American Journal of Physiology·L L Protas, G R Leontieva
Nov 1, 1995·The American Journal of Physiology·P C Hou, W W Burggren
Apr 29, 1997·Proceedings of the National Academy of Sciences of the United States of America·K BakerM C Fishman
May 1, 1999·Physiological and Biochemical Zoology : PBZ·A Jacobsson, R Fritsche
Feb 22, 2000·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·J Altimiras
Oct 26, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·G SchönwegerB Pelster
Nov 18, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·R FritscheB Pelster
Sep 14, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·E JacobB Pelster
May 3, 2003·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Thorsten Schwerte, Regina Fritsche

❮ Previous
Next ❯

Citations

Jan 5, 2011·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Shelby L SteeleSteve F Perry
Mar 10, 2012·Toxicological Sciences : an Official Journal of the Society of Toxicology·Kevin A LanhamWarren Heideman
Aug 22, 2015·Expert Opinion on Drug Discovery·Mirjam KeßlerSteffen Just
Nov 13, 2012·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Lene H PetersenDuane B Huggett
Sep 20, 2011·Autonomic Neuroscience : Basic & Clinical·Erik Sandblom, Michael Axelsson
Jan 12, 2011·Biochemical and Biophysical Research Communications·Jian Xu, Fu-kang Xie
Mar 30, 2010·Autonomic Neuroscience : Basic & Clinical·Heather M YoungColin R Anderson
Nov 2, 2015·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Kimberly M Mitchell, Thomas W Moon
Jun 15, 2011·Birth Defects Research. Part C, Embryo Today : Reviews·Lasse Dahl JensenYihai Cao
Apr 9, 2010·Alcoholism, Clinical and Experimental Research·Cynthia A Dlugos, Richard A Rabin
Feb 26, 2015·The Journal of Comparative Neurology·Matthew R StoyekFrank M Smith
Mar 26, 2013·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Triantafyllia OrfanidouGeorge Theophilidis
Aug 11, 2011·General and Comparative Endocrinology·Emma GiltrowMariann Rand-Weaver
Jun 4, 2016·International Journal of Molecular Sciences·Eric J MersereauTristan Darland
Mar 12, 2016·PloS One·Daniel BrönnimannValentin Djonov
Sep 15, 2009·Toxicology Mechanisms and Methods·Dong-Jae KimJae-Hak Park
Jun 12, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Shelby L SteeleSteve F Perry
Feb 5, 2010·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Kara D MannPatrick S Page-McCaw
Nov 26, 2008·Journal of Biomolecular Screening·Khadijah MakkyAlan N Mayer
Jul 6, 2020·The Journal of Experimental Biology·Naim M BautistaWarren Burggren
Sep 3, 2019·Frontiers in Pharmacology·Luigi Margiotta-CasaluciMatthew J Winter
Oct 23, 2019·Molecular Biology Reports·Julia Torres-VelardeAlejandra García-Gasca
Sep 16, 2020·International Journal of Molecular Sciences·Jussep Salgado-AlmarioJuan Llopis
Jun 26, 2014·The Journal of Biological Chemistry·Yixuan ZhangHua Cai
Jun 16, 2017·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Jamie K HarringtonKimara L Targoff
Feb 14, 2021·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·M C Hughes, S F Perry
Apr 15, 2011·The Journal of Experimental Biology·Shelby L SteeleSteve F Perry
Jul 22, 2021·Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology·William Joyce, Steve F Perry
Jul 7, 2021·Scientific Reports·Satishkumar SubendranChia-Yuan Chen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adrenergic Receptors: Trafficking

Adrenergic receptor trafficking is an active physiological process where adrenergic receptors are relocated from one region of the cell to another or from one type of cell to another. Discover the latest research on adrenergic receptor trafficking here.