Development of the urodynamic pattern in infants with myelomeningocele

British Journal of Urology
U SillénU Jodal

Abstract

To study changes in the urodynamic pattern during the first year of life in patients with myelomeningocele (MMC) and to correlate these to deleterious effects on the upper urinary tract. methods Thirty-four infants with MMC were investigated using cystometry, micturating cystourethrography and urography at 1, 4 and 10 months of age. Detrusor contractility was characterized by an increase in activity, with hyper-reflexia in 45% initially, increasing to 65% at the 4-month investigation. During the same period, the number of infants with areflexia decreased from 25% to 12%. Between 4 and 10 months, there were only minor changes in detrusor contractility. The number of patients with poorly compliant bladders also increased between the first and fourth month. The number of patients with elevated outlet resistance increased only slightly during the first year, from 32% of all infants at the initial investigation to 40% at the 10-month follow-up. Vesico-ureteric reflux was detected in 12 of the patients during the year, with five already diagnosed at the first investigation. Almost all refluxes were cured with clean intermittent catheterization, with additional pharmacological therapy in two patients; one patient required a vesicostom...Continue Reading

Citations

Oct 25, 2008·Journal of Pediatric Urology·L V SwithinbankP Abrams
Jun 2, 2012·Journal of Pediatric Urology·Stavros CharalampousFotios Papacristou
Feb 24, 2009·The Journal of Urology·Bettina JorgensenTroels Munch Jorgensen
Jun 24, 2010·The Urologic Clinics of North America·Warren T Snodgrass, Patricio C Gargollo
Nov 9, 2006·Advances in Pediatrics·W Lane M Robson, Alexander K C Leung
Sep 2, 2006·The Journal of Urology·Luis Antonio GuerraMichael Leonard
Aug 18, 2004·The Urologic Clinics of North America·Warren T Snodgrass, Richard Adams
Mar 2, 2010·Scandinavian Journal of Urology and Nephrology·Bettina JørgensenTroels Munch Jørgensen
Dec 6, 2001·Current Opinion in Urology·R J Nijman
Nov 20, 2016·Neurourology and Urodynamics·Maya HorstRita Gobet
Apr 25, 2020·World Journal of Urology·John S WienerRaimund Stein

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