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Developmental changes in expression and self-editing of adenosine deaminase type 2 pre-mRNA and mRNA in rat brain and cultured cortical neurons

Neuroscience Research

Jun 7, 2008

Pham Nguyet Thi HangKinzo Matsumoto

Abstract

Adenosine deaminase-1 and -2 (ADAR-1 and -2) are double-stranded RNA-specific enzymes involved in the editing of genes including serotonin 2C receptor (5-HT2CR) mRNA and ADAR-2 pre-mRNA. We reported that the editing efficacy of 5-HT2CR mRNA altered during brain development in rats. The ...read more

Mentioned in this Paper

Embryo
Exons
Adenosine
Pellet Formation
Enzymes, antithrombotic
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Primary RNA Transcript
RNA, Double-Stranded
Neurons
Inosine
Paper Details
References
  • References28
  • Citations11
12

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Developmental changes in expression and self-editing of adenosine deaminase type 2 pre-mRNA and mRNA in rat brain and cultured cortical neurons

Neuroscience Research

Jun 7, 2008

Pham Nguyet Thi HangKinzo Matsumoto

PMID: 18534702

DOI: 10.1016/j.neures.2008.04.007

Abstract

Adenosine deaminase-1 and -2 (ADAR-1 and -2) are double-stranded RNA-specific enzymes involved in the editing of genes including serotonin 2C receptor (5-HT2CR) mRNA and ADAR-2 pre-mRNA. We reported that the editing efficacy of 5-HT2CR mRNA altered during brain development in rats. The ...read more

Mentioned in this Paper

Embryo
Exons
Adenosine
Pellet Formation
Enzymes, antithrombotic
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Primary RNA Transcript
RNA, Double-Stranded
Neurons
Inosine

Similar Papers Found In These Feeds

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Paper Details
References
  • References28
  • Citations11
12
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