PMID: 2497785May 31, 1989Paper

Developmental changes in galactosyltransferase activity in the rat small intestine

Biochimica Et Biophysica Acta
C K OzakiW A Walker

Abstract

During postnatal development, UDP-Gal: GlcNAc(beta 1-4)-galactosyltransferase (4 beta-GT) and UDP-Gal:GalNAc(beta 1-3)-galactosyltransferase (3 beta-GT) activities were increased by 17- and 24-fold, respectively, in the rat small intestine. The injection of cortisone into suckling rats resulted in precocious induction of distal 4 beta- and 3 beta-GT activities by 2.7- and 1.8-fold, respectively. Injection of phorbol-12-myristate-13-acetate (PMA) resulted in precocious induction of distal 3 beta-GT by 2.7-fold. These results suggest that intestinal galactosyltransferase activities are under developmental regulation and can be modified by cortisone and PMA.

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Citations

May 7, 2003·The Journal of Steroid Biochemistry and Molecular Biology·Marie-Claire Biol-N'garagbaPierre Louisot
May 24, 2000·Proceedings of the National Academy of Sciences of the United States of America·N N NanthakumarW A Walker
Sep 29, 2007·American Journal of Physiology. Gastrointestinal and Liver Physiology·Sonoko NarisawaJosé Luis Millán
Jun 26, 2002·Journal of Pediatric Gastroenterology and Nutrition·W Allan Walker
Apr 5, 2000·Journal of Pediatric Gastroenterology and Nutrition·D DaiW A Walker
Jun 2, 2001·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·E C Claud, W A Walker
Mar 18, 2000·The Journal of Nutrition·U Shah, W A Walker

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