PMID: 3756216Oct 1, 1986Paper

Developmental changes in the activities of sialyl- and fucosyltransferases in rat small intestine

Biochimica Et Biophysica Acta
S H Chu, W A Walker

Abstract

To study an enzymatic basis for the postnatal changes in intestinal glycosylation, the activities of sialyl- and fucosyltransferases were determined in the particulate fraction of mucosal cells prepared from rat small intestine of various ages. The results show that sialyltransferase activity was present in increased levels compared to adults during the preweaning period (1-2 weeks) and subsequently declined 5-fold to adult levels after weaning, while fucosyltransferase activity was decreased compared to adults in the first 3 weeks of life, rapidly increased at 4 weeks, and reached adult levels (10-fold) by 5 weeks. The changes in both sialyl- and fucosyltransferase activities were reflected by the membranous content of glycosidic-bound sialic acid and fucose, respectively. Cortisone injection precociously induced a decreased sialyltransferase activity and an increased fucosyltransferase activity in 2-week-old suckling rats. This study indicates that the activities of sialyl- and fucosyltransferases were reciprocally related and modulated by cortisone action in the developing intestine. These enzyme changes may be responsible for the previously noted shift from sialylation to fucosylation of the intestinal mucosa during maturat...Continue Reading

References

Aug 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·R A MulivorH Harris
Mar 1, 1976·Archives of Biochemistry and Biophysics·M M MadappallyE F Zimmerman
Apr 1, 1977·Analytical Biochemistry·G C Tsay, G Dawson
Jan 1, 1985·Annual Review of Physiology·S J Henning
Jan 1, 1983·Critical Reviews in Microbiology·G W Jones, R E Isaacson
Mar 1, 1982·The Journal of General Virology·N J Dimmock
Aug 13, 1962·Biochimica Et Biophysica Acta·R G DOELL, N KRETCHMER

❮ Previous
Next ❯

Citations

Dec 2, 1999·Biochimica Et Biophysica Acta·E StaudacherL März
Sep 17, 1999·Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie·S GrécoM C Biol
May 7, 2003·The Journal of Steroid Biochemistry and Molecular Biology·Marie-Claire Biol-N'garagbaPierre Louisot
Jun 5, 2002·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Ming Z FanDale King
May 5, 2004·Proceedings of the National Academy of Sciences of the United States of America·Erika C ClaudBobby J Cherayil
Mar 26, 2003·Glycobiology·Daniel J Becker, John B Lowe
May 16, 2014·Nutrition Reviews·Sandra J M ten BruggencateMargriet H C Schoterman
Feb 19, 2014·Pathophysiology : the Official Journal of the International Society for Pathophysiology·Jegen KandasamyTamas Jilling
Jan 23, 2016·Digestive Diseases and Sciences·Sana RokhsefatElena M Comelli
Mar 8, 2011·Anaerobe·Erika C Claud
Dec 3, 2014·The American Journal of Pathology·Scott M TannerColin A Martin
Jul 7, 2009·Annual Review of Nutrition·Bing Wang
Nov 18, 2005·European Journal of Gastroenterology & Hepatology·Jonathan E Teitelbaum, W Allan Walker
Jun 4, 2008·Journal of Clinical Gastroenterology·Erika C Claud, W Allan Walker
Aug 4, 2007·American Journal of Physiology. Gastrointestinal and Liver Physiology·Di MengN Nanda Nanthakumar
Oct 14, 2011·Journal of Clinical Gastroenterology·Kriston Ganguli, W Allan Walker
Jun 2, 2001·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·E C Claud, W A Walker
Dec 12, 2002·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·N Nanda NanthakumarW Allan Walker
Jun 20, 2003·Cellular Microbiology·M I FernandezP J Sansonetti
Feb 14, 2002·American Journal of Physiology. Gastrointestinal and Liver Physiology·Dingwei DaiW Allan Walker
Jan 1, 1988·Nutrition Reviews·N F Sheard, W A Walker
Aug 21, 2008·Molecular and Cellular Biochemistry·Kamaljit Kaur ChaudhryAkhtar Mahmood
Jul 18, 2002·American Journal of Physiology. Gastrointestinal and Liver Physiology·Kayo ArimaFayez K Ghishan
Aug 5, 1987·Biochimica Et Biophysica Acta·O P SrivastavaR Torres-Pinedo
May 31, 1989·Biochimica Et Biophysica Acta·C K OzakiW A Walker
May 31, 1988·Biochemical and Biophysical Research Communications·S W ChJ F Burke

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.