PMID: 9641524Jun 26, 1998Paper

Developmental expression of nitric oxide synthase in the rat diencephalon with special reference to the thalamic paratenial nucleus

International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience
O GorbatyukT Hökfelt

Abstract

Using immunohistochemistry and in situ hybridization the distribution of nitric oxide synthase (NOS) was investigated in the rat brain during pre- and postnatal development. At E15 weak NOS-like immunoreactivity (NOS-LI) could be seen in the differentiation field of the anterior hypothalamus. At E17 strong NOS-LI was observed in the developing neurons of the hypothalamic paraventricular nucleus, supraoptic nucleus, anterodorsal nucleus and lateral hypothalamic areas. In the thalamic paratenial nucleus a strong NOS-LI was observed in these neurons at E17, E18 and P1 with a weaker intensity at P3, P7, P9 and P15, whereas at P30 and in adult rats no NOS-positive neurons could be detected. NOS expression at E17 and P3 was verified by in situ hybridization. These results suggest that NO may have a developmental role at least in one of the regions studied, the thalamic paratenial nucleus.

References

Jan 1, 1992·Neuroscience·S R Vincent, H Kimura
Jan 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·D S Bredt, S H Snyder
Apr 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·B T HopeS R Vincent
Sep 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·T M DawsonS H Snyder
Mar 1, 1988·Trends in Neurosciences·J G Parnavelas, M E Cavanagh
Oct 17, 1989·European Journal of Pharmacology·J GarthwaiteS Moncada
Nov 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·D S Bredt, S H Snyder
Apr 1, 1989·Experimental Neurology·R D SkinnerE Garcia-Rill
Jun 30, 1988·Biochemical and Biophysical Research Communications·R M PalmerS Moncada
Jun 1, 1983·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·J L Platt, A F Michael
Sep 16, 1994·Brain Research. Developmental Brain Research·G GiuiliG Guellaën
Jun 1, 1995·Alcoholism, Clinical and Experimental Research·R A Baker, W J Shoemaker
Apr 2, 1993·Neuroscience Letters·P Derer, M Derer
Jun 8, 1993·Brain Research. Developmental Brain Research·T MatsumotoU Förstermann
Nov 19, 1993·Brain Research. Developmental Brain Research·T González-HernándezG Meyer
Oct 27, 1995·Brain Research. Developmental Brain Research·D RicheM Denavit-Saubié
Dec 1, 1995·Journal of Neuroscience Research·F TenórioR Mendez-Otero
Jul 18, 1997·Brain Research. Developmental Brain Research·E García-OjedaJ Aijón

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Citations

Jun 20, 2001·Brain Research. Developmental Brain Research·H TeradaK Kitahama
Apr 4, 2006·Zhurnal evoliutsionnoĭ biokhimii i fiziologii·E V ChernigovskaiaM V Glazova
Feb 24, 2001·Hypertension Research : Official Journal of the Japanese Society of Hypertension·T NakataM Nakagawa
Feb 10, 2004·The Journal of Experimental Biology·B HolmqvistP Alm

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