Developmental neuropsychological assessment of 4- to 5-year-old children born following Preimplantation Genetic Diagnosis (PGD): A pilot study

Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence
Gilat Chaya SacksTalia Eldar-Geva

Abstract

The purpose of this pilot study was to evaluate developmental neuropsychological profiles of 4- to 5-year-old children born after Preimplantation Genetic Diagnosis (PGD). Twenty-seven participants received a neurological examination and a battery of neuropsychological assessments including Wechsler Preschool & Primary Scale of Intelligence - Third Edition (WPPSI-III; cognitive development), Preschool Language Scale, Fourth Edition (PLS-4; language development), Wide Range Assessment of Visual Motor Abilities (visual motor abilities), Childhood Autism Rating Scales II (a screening test for autistic spectrum disorders), and the Miles ABC Test (ocular dominance). Parental questionnaires included the Behavior Rating Inventory of Executive Function Preschool Version (BRIEF-P; executive function), Child Behavior Checklist (CBCL) and the Carey Temperament Scales Behavioral Style Questionnaire (socioemotional development and temperament), and the Vineland Adaptive Behavior Scales, Interview Edition, Second Edition (general adaptive behavior). Subjects' tests results were compared to each test's norms. Children born after PGD demonstrated scores within the normal or above-normal ranges for all developmental outcomes (mean ± SD): WPPSI-I...Continue Reading

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Citations

Nov 28, 2019·Human Reproduction Update·Megan Leaver, Dagan Wells
Feb 23, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Despina D Briana, Ariadne Malamitsi-Puchner
Sep 29, 2018·Human Reproduction·M HeijligersC E M de Die-Smulders
Aug 6, 2020·Genes·Martine De Rycke, Veerle Berckmoes
Sep 9, 2021·Molecular Diagnosis & Therapy·Alice RogersTristan Hardy

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Methods Mentioned

BETA
biopsy

Software Mentioned

SPSS

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