Developmental regulation of Chlamydia trachomatis class I accessible protein-1, a CD8+ T cell antigen

The Journal of Infectious Diseases
Zarine R BalsaraMichael N Starnbach

Abstract

In this report, we show that the Chlamydia trachomatis-specific CD8+ T cell antigen class I accessible protein-1 (Cap1) is expressed during the early stages of the C. trachomatis developmental cycle. We provide additional evidence suggesting that Cap1 may be important in early immune recognition of the organism. Understanding the temporal and spatial expression of CD8+ T cell antigens such as Cap1 may be beneficial in designing multisubunit vaccines to stimulate a vigorous immune response against C. trachomatis.

Citations

Oct 16, 2009·Veterinary Microbiology·Delphine Sylvie Anne Beeckman, Daisy C G Vanrompay
Mar 10, 2015·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Vítor Borges, João Paulo Gomes
Sep 16, 2008·Microbes and Infection·Benjamin WizelAmy Tvinnereim
Feb 16, 2008·Veterinary Research·Delphine Sylvie Anne BeeckmanDaisy C G Vanrompay
Apr 17, 2019·Infection and Immunity·Jennifer D Helble, Michael N Starnbach

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