Developmental regulation of human globin genes

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Developmental regulation of human globin genes

Abstract

Citations

Homology of a 130-kb region enclosing the alpha-globin gene cluster, the alpha-locus controlling region, and two non-globin genes in human and mouse

Butyrate-induced reactivation of the fetal globin genes: a molecular treatment for the beta-hemoglobinopathies

Hematological responses to hydroxyurea therapy in multitransfused thalassemic children

Detection of non-deletional type of hereditary persistence of fetal hemoglobin (HPFH) condition associated with 619 bp β(°)-thalassemia deletion

Organization of a β and α globin gene set in the teleost Atlantic cod, Gadus morhua

TCR V beta genes in man and mouse and the factors that shape the linkage pattern of immune receptor genes

Role of butyric acid and its derivatives in the treatment of colorectal cancer and hemoglobinopathies

Biological, cellular, and molecular characteristics of an inducible transgenic skin tumor model: a review

Hemoglobin Bart's disease in an Italian boy. Interaction between alpha-thalassemia and hereditary persistence of fetal hemoglobin

A short-term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders

A gene deletion ending within a complex array of repeated sequences 3' to the human beta-globin gene cluster

The modulation of Hb F synthesis in adult erythroid progenitor (burst-forming unit) cultures reflects changes in gamma-globin gene transcription and chromatin structure

A developmentally stable chromatin structure in the human beta-globin gene cluster

Structure and expression of the rat neuropeptide Y gene

Retroviral-mediated transfer of genomic globin genes leads to regulated production of RNA and protein

Molecular analysis of the human beta-globin locus activation region

Protein-DNA interactions in vivo of an erythroid-specific, human beta-globin locus enhancer

Functional erythroid promoters created by interaction of the transcription factor GATA-1 with CACCC and AP-1/NFE-2 elements

Transcriptional activation of human adult alpha-globin genes by hypersensitive site-40 enhancer: function of nuclear factor-binding motifs occupied in erythroid cells

Isolation, sequence, and differential expression of a human K7 gene in simple epithelial cells.

Expression of the neutrophil elastase gene during human bone marrow cell differentiation

The gammaPE complex contains both SATB1 and HOXB2 and has positive and negative roles in human gamma-globin gene regulation

A silent deletion in the beta-globin gene cluster

Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids

Erythroid specific activation of the Xenopus laevis adult alpha-globin promoter in transient heterokaryons

Mutations in two regions upstream of the A gamma globin gene canonical promoter affect gene expression.

A novel C-T transition within the distal CCAAT motif of the G gamma-globin gene in the Japanese HPFH: implication of factor binding in elevated fetal globin expression

Developmentally regulated and erythroid-specific expression of the human embryonic beta-globin gene in transgenic mice

Enhancer activity of HS2 of the human beta-LCR is modulated by distance from the key nucleosome

Evolution of hemoglobin and its genes

DNA haplotype heterogeneity of beta-thalassaemia in Greece: feasibility of prenatal diagnosis

Activation of the human beta-globin promoter in K562 cells by DNA sequences 5' to the fetal gamma- or embryonic zeta-globin genes

Transcriptional activation and DNase I hypersensitive sites are associated with selective expression of the gastrin-releasing peptide gene

Foetal haemoglobin and the dynamics of paediatric malaria

Taking the good out of the bad: lentiviral-based gene therapy of the hemoglobinopathies

Ancestral hemoglobin switching in lampreys

Genetic determinants of β-thalassemia intermedia in Pakistan

Multiple linked β and α globin genes in Atlantic cod: A PCR based strategy of genomic exploration

Laboratory diagnosis of hemoglobinopathies

Reciprocal regulation of acetylcholinesterase and butyrylcholinesterase in mammalian skeletal muscle

Molecular analysis of deletions in the human beta-globin gene cluster: deletion junctions and locations of breakpoints.

The human class I alcohol dehydrogenase gene cluster: three genes are tandemly organized in an 80-kb-long segment of the genome

A cluster of expressed zinc finger protein genes in the pericentromeric region of human chromosome 10

Chromosomal localization of seven neuronal nicotinic acetylcholine receptor subunit genes in humans

Rapid reprogramming of globin gene expression in transient heterokaryons

Identification of deletion mutations and three new genes at the familial polyposis locus

HbF in HbE/β-thalassemia: A clinical and laboratory correlation

A 2-Mb YAC contig and physical map of the natural killer gene complex on mouse chromosome 6

Abrogation of IL-3 requirements and stimulation of hematopoietic cell proliferation in vitro and in vivo by carboxylic acids

The human GCAP1 and GCAP2 genes are arranged in a tail-to-tail array on the short arm of chromosome 6 (p21.1)

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