Developmental regulation of juvenile hormone biosynthesis by the ring gland of Drosophila melanogaster

Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
D S RichardL I Gilbert

Abstract

The synthesis in vitro of the putative dipteran juvenile hormone (JHB3) by ring glands isolated from third instar Drosophila melanogaster larvae was quantified by a radiochemical assay. The data indicate that JHB3 synthesis is developmentally regulated during the period prior to wandering until after puparium formation. The highest level of basal production occurred during the postfeeding stage, and synthesis declined after pupariation. Similar relative profiles of synthesis were obtained upon the addition of the JHB3 precursor, farnesoic acid, although the absolute levels of production were elevated considerably. Basal JHB3 production by brain-ring gland complexes in vitro was also highest during the postfeeding stage, although the synthetic rates were much lower than displayed by isolated ring glands. Further analysis revealed that methyl farnesoate, a JHB3 precursor, was synthesized by brain-ring gland complexes in significant quantity. A dual mechanism of brain-centered control of JHB3 biosynthesis is proposed.

References

Feb 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·D S RichardL I Gilbert
Jan 1, 1987·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·V C HenrichL I Gilbert
Nov 1, 1986·Molecular and Cellular Endocrinology·M Gadot, S W Applebaum

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Citations

Aug 28, 2020·Frontiers in Cell and Developmental Biology·Lynn M Riddiford
Jan 1, 1995·Archives of Insect Biochemistry and Physiology·P Moshitzky, S W Applebaum
Mar 1, 1993·Roux's Archives of Developmental Biology : the Official Organ of the EDBO·Ji-da Dai, Lawrence I Gilbert
Oct 1, 1991·Molecular and Cellular Endocrinology·M AltaratzD Segal
May 1, 1991·General and Comparative Endocrinology·L M Riddiford, M Ashburner
Jul 14, 2007·Insect Biochemistry and Molecular Biology·Davy Jones, Grace Jones
Aug 12, 2008·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Penny M HopkinsTracy Washington
Jul 15, 2009·General and Comparative Endocrinology·Davy JonesJean-Rene Martin
Jun 15, 2010·Journal of Insect Physiology·Grace JonesJean-Rene Martin

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