Developmental toxicity study of 60 Hz (power frequency) magnetic fields in rats

Teratology
B M RyanD L McCormick

Abstract

Considerable public concern has developed regarding possible adverse reproductive outcomes resulting from exposure to power frequency magnetic fields (MF). To identify possible effects of MF exposure on fetal development, timed-pregnant female Sprague-Dawley rats (55/ group) received continuous exposure to linearly polarized, transient-free 60 Hz MF at field strengths of 0 Gauss (G; sham control), 0.02 G, 2 G, or 10 G, or intermittent (1 hr on/1 hr off) exposure to 10 G fields. Dams received MF or sham exposures for 18.5 hr/day on gestation days 6 through 19. A positive control group of 15 dams received daily oral doses of 85 mg ethylenethiourea (ETU)/kg body weight on gestation days 11, 12, and 13; positive control dams received no MF exposure. Ambient and experimentally generated MF were monitored continuously throughout the study. Experimentally generated MF were within 2% of the target field strengths at all times, and ambient MF to which sham controls were exposed did not exceed 0.7 mG at any point in the study. No evidence of maternal toxicity was identified in any MF-exposed dam; mean maternal body weight and organ weights in groups exposed to MF did not differ from those in sham controls. Comparisons of fetal viability ...Continue Reading

References

Apr 1, 1990·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·D N RommereimL E Anderson
Jan 1, 1987·Bioelectromagnetics·W T KauneD B Thomas
Jan 1, 1987·Bioelectromagnetics·M R SikovR D Phillips
Jan 1, 1986·Bioelectromagnetics·N Wertheimer, E Leeper
Jan 1, 1984·Teratogenesis, Carcinogenesis, and Mutagenesis·J L Stuckhardt, S M Poppe
Nov 1, 1993·Reproductive Toxicology·R L BrentD A Beckman

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Citations

Jul 23, 2005·Bioelectromagnetics·Jukka Juutilainen
Jan 14, 2009·Bioelectromagnetics·Hae-June LeeYun-Sil Lee
Nov 24, 2005·Bioelectromagnetics·Moh'd-Ali Al-AkhrasAhmed Elbetieha
Oct 14, 2011·Neuromodulation : Journal of the International Neuromodulation Society·Donald J BernardiniThomas T Simopoulos
Dec 16, 1998·Bioelectromagnetics·H HuuskonenH Komulainen
Jul 17, 2004·Health Physics·UNKNOWN International Commission on Non-Ionizing Radiation Protection

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