Developmental tuning of mineralization drives morphological diversity of gill cover bones in sculpins and their relatives

Evolution Letters
Eli G CytrynbaumCharles B Kimmel

Abstract

The role of osteoblast placement in skeletal morphological variation is relatively well understood, but alternative developmental mechanisms affecting bone shape remain largely unknown. Specifically, very little attention has been paid to variation in later mineralization stages of intramembranous ossification as a driver of morphological diversity. We discover the occurrence of specific, sometimes large, regions of nonmineralized osteoid within bones that also contain mineralized tissue. We show through a variety of histological, molecular, and tomographic tests that this "extended" osteoid material is most likely nonmineralized bone matrix. This tissue type is a significant determinant of gill cover bone shape in the teleostean suborder Cottoidei. We demonstrate repeated evolution of extended osteoid in Cottoidei through ancestral state reconstruction and test for an association between extended osteoid variation and habitat differences among species. Through measurement of extended osteoid at various stages of gill cover development in species across the phylogeny, we gain insight into possible evolutionary developmental origins of the trait. We conclude that this fine-tuned developmental regulation of bone matrix mineraliza...Continue Reading

References

Nov 1, 1992·Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission·Z A Ralis, G Watkins
Mar 14, 1998·Calcified Tissue International·E A CowlesG A Gronowicz
May 6, 2003·Developmental Biology·Louis-Bruno RuestDavid E Clouthier
Jan 22, 2004·Bioinformatics·Emmanuel ParadisKorbinian Strimmer
Feb 21, 2004·Biochemical and Biophysical Research Communications·Ryo FukuyamaToshihisa Komori
Apr 8, 2004·Proceedings of the National Academy of Sciences of the United States of America·William A CreskoJohn H Postlethwait
Jul 23, 2004·Birth Defects Research. Part C, Embryo Today : Reviews·David E Clouthier, Thomas F Schilling
Apr 13, 2005·Proceedings of the National Academy of Sciences of the United States of America·Charles B KimmelWilliam A Cresko
Sep 7, 2005·Cell·Loning FuGerard Karsenty
Nov 1, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Tamara A Franz-OdendaalP Eckhard Witten
May 23, 2006·Trends in Ecology & Evolution·Paul M Brakefield
May 12, 2007·Evolution; International Journal of Organic Evolution·Kerry B Marchinko, Dolph Schluter
May 19, 2007·Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission·M B Walker, C B Kimmel
Nov 17, 2007·Bioinformatics·Luke J HarmonWendell Challenger
Sep 13, 2008·Evolution; International Journal of Organic Evolution·Brian Sidlauskas
Nov 11, 2008·Proceedings. Biological Sciences·Milica MandicJeffrey G Richards
Jan 24, 2009·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Nan LiHenry H Roehl
Apr 29, 2009·Expert Opinion on Therapeutic Targets·Ichiro TakadaShigeaki Kato
Aug 12, 2009·Evolution; International Journal of Organic Evolution·Liam J Revell
Jan 8, 2010·BMC Evolutionary Biology·R Craig AlbertsonJohn H Postlethwait
Jan 19, 2010·Proceedings of the National Academy of Sciences of the United States of America·Erica Bree RosenblumHopi E Hoekstra
Mar 12, 2010·PloS One·Charles B KimmelMarcie McFadden
May 17, 2011·Nature Biotechnology·Manfred G GrabherrAviv Regev
Jul 19, 2011·Journal of Bone and Mineral Metabolism·Tadahiro IimuraAkira Yamaguchi
Jan 27, 2012·Evolution; International Journal of Organic Evolution·Charles B KimmelKatrina McGuigan
Mar 21, 2012·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Kyoung Min KimSung-Kil Lim
Oct 2, 2012·Neural Computation·Victor Solo, Syed Ahmed Pasha
Oct 27, 2012·Molecular Phylogenetics and Evolution·Matthew L Knope
Jan 16, 2013·Journal of Evolutionary Biology·M L Knope, J A Scales
Jun 7, 2013·Nature Communications·Daniel L RaboskyMichael E Alfaro
Oct 9, 2013·Ecology and Evolution·Laura A B WilsonMarcelo R Sánchez-Villagra
Sep 12, 2015·Proceedings. Biological Sciences·Jie ChengArne W Nolte

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Methods Mentioned

BETA
PCR
PCA
PCAs

Software Mentioned

R package phytools
R package rptR
BLAST
Adobe Photoshop
Trinity
R package nlme
PGLS
R package convevol
R Core Team
fasta

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.