PMID: 2367Feb 6, 1976

Developmental variations of tyrosine hydroxylase and acetylcholinesterase in embryonic and post-hatching chicken sympathetic ganglia

Brain Research
K FairmanV Chiappinelli

Abstract

The developmental variations of tyrosine hydroxylase (TH) and of acetylcholinesterase (AChE) were studied in embryonic and post-hatching chicken sympathetic ganglia. Different levels of TH activity were found in two different flocks of White Leghorn chicken, which are probably dependent on genetic differences. These enzymatic differences, however, do not become apparent before hatching and may indicate a combined effect of genetic variation and functional demands. During the period of incubation, TH activity is characterized by a pronounced and steady increase from the twelfth day of incubation up to day 2 after hatching. This corresponds to a period of intense maturation of the sympathetic neuron. In the period following hatching, the 'fourth day fall phenomenon' previously described by us for DOPA decarboxylase (DDC), dopamine-beta-hydroxylase (DBH), and monoamine oxidase (MAO) is not seen in the TH curve. Instead, TH activity tends to remain constant between days 2 and 14 after hatching (ah). Both ganglionic protein and weight remain constant in this period, indicating a phase of general pause in protein synthesis. AChE activity increases steadily from the eighth until the twenty-first day of incubation. A sudden and signifi...Continue Reading

References

May 1, 1973·Journal of Neurochemistry·G F Wooten, J T Coyle
Jun 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·P B MolinoffJ Axelrod
Jun 1, 1971·Acta Physiologica Scandinavica·E Giacobini, B Noré
Nov 1, 1969·Journal of Neurochemistry·S H Koslow, E Giacobini
Apr 1, 1967·Acta Physiologica Scandinavica·E GiacobiniF Sjöqvist
Jan 1, 1951·Journal of Morphology·V HAMBURGER, H L HAMILTON

Citations

Jan 1, 1983·Journal of Neural Transmission·T S ElizanM D Yahr
Nov 10, 1980·Brain Research·D W Hoffman, E Giacobini
Jul 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·A M Cohen

Related Concepts

Acetylthiocholinesterase
Chick Embryo
Autonomic Ganglion
Gestational Age
Synapses
Tyrosine 3-Monooxygenase

Related Feeds

Brain developing: Influences & Outcomes

This feed focuses on influences that affect the developing brain including genetics, fetal development, prenatal care, and gene-environment interactions. Here is the latest research in this field.