Developments in ocular allergy

Current Opinion in Allergy and Clinical Immunology
Shayla L Chambless, Stefan Trocme

Abstract

The goal of this article is to evaluate developments in the knowledge of inflammatory mechanisms and treatments of ocular allergy. Research developments in ocular allergy summarized in this article include the following findings: (1) ocular epithelial cells play a role in inflammation; (2) respiratory syncytial virus is a pathogen in allergic conjunctivitis; (3) transglutaminase inhibitors reverse allergic related inflammation; (4) eosinophils and neutrophils both play a role in ocular allergy; (5) eotaxin-1 and eotaxin-2 play a role in eosinophilic recruitment; and (6) loteprednol etabonate, desonide phosphate, and cyclosporine have been shown to be effective and safe in the treatment of ocular allergy. This article summarizes the research conducted for each of the above recent findings and outlines their clinical applications.

References

Sep 25, 2002·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Neri PucciAlberto Vierucci
Dec 10, 2002·American Journal of Ophthalmology·Elisabeth M MessmerAnselm Kampik
Mar 8, 2003·Ophthalmology·Andrea LeonardiVirginia L Calder
Jul 18, 2003·Current Eye Research·S D TrocmeC H Dohlman

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Citations

Apr 5, 2005·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·E M Messmer
Apr 27, 2012·International Journal of Inflammation·Timothy L Comstock, Heleen H Decory
May 7, 2015·Expert Opinion on Pharmacotherapy·Mark B AbelsonLisa M Smith
Jun 4, 2015·Current Medical Research and Opinion·Lian-Qun WuRui-Li Wei
Nov 10, 2011·Acta Ophthalmologica·Brett P BieloryLeonard Bielory
Sep 19, 2006·Biochimica Et Biophysica Acta·Saul YedgarDavid Shoseyov
May 31, 2006·Expert Opinion on Pharmacotherapy·Bita ManzouriRichard Wyse
Sep 7, 2006·Current Opinion in Allergy and Clinical Immunology·Masato KuboAtsuki Fukushima
Sep 14, 2012·The Cochrane Database of Systematic Reviews·Julio J González-LópezGema Rebolleda Fernández
Sep 10, 2020·Drug Delivery and Translational Research·Sherif A GaballaHamdy Abdelkader

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