Developments of nano-TiO2 incorporated hydroxyapatite/PEEK composite strut for cervical reconstruction and interbody fusion after corpectomy with anterior plate fixation

Journal of Photochemistry and Photobiology. B, Biology
Fanlei KongJiangfeng Ji

Abstract

The technique of anterior cervical corpectomy and fusion (ACCF) for strut grafting has become a widespread and actively applied for many cervical complaints including cervical degeneration of the intervertebral disks, cervical trauma, cancer, rheumatoid arthritis and multilevel cervical spondylotic diseases. To avoid the complications of the old techniques, the construct stability and long anterior screw-plate designs of the bone strut have been improved by using effective biomaterials. The nanostructured hydroxyapatite (HAp) incorporated with biocompatible polymer matrixes is an effective biomedical material and creating a functional properties applied for different tissue replacements such as dental, hips, knees, tendon and ligaments and tissue repair for maxillofacial reconstruction, stabilization of the jaw bone and spinal fusion. In the present investigation, we have successfully designed cylindrical nano titanium dioxide (n-TiO2) interbody fusion with anterior plate fixation. The n-TiO2 incorporated HAp/ Polyetheretherketone (PEEK) nanocomposite strut has a superior mechanical properties and larger contact area with high fusion rates as compared with the HAp/PEEK strut in the absence of n-TiO2 nanoparticles. It is highly ...Continue Reading

Citations

Feb 14, 2020·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Fatih Erdem Baştan
Nov 7, 2019·Neurospine·Andrew WarburtonSamuel K Cho
Mar 10, 2021·Journal of Tissue Engineering and Regenerative Medicine·Hai LiuDaozhang Cai
Apr 18, 2021·Colloids and Surfaces. B, Biointerfaces·Bankole I OladapoFrancis T Omigbodun
Sep 10, 2021·ACS Biomaterials Science & Engineering·Shrinath BhatMahaveer D Kurkuri
Nov 27, 2021·Environmental Science and Pollution Research International·Filomena MottolaLucia Rocco
Dec 4, 2021·Journal of Biomaterials Science. Polymer Edition·Mugilan Thanigachalam, Aezhisai Vallavi Muthusamy Subramanian

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