PMID: 9442986Jan 1, 1997Paper

Dexfenfluramine for weight gain secondary to psychotropics

Depression and Anxiety
P S Masand, S Gupta

Abstract

We describe the use of dexfenfluramine (Redux) in six patients with mood disorders (bipolar disorder = 3; major depression = 3) who developed significant weight gain as a result of their psychotropics. All patients were females with an age range of 27-58 years. The duration of the trial varied from 3 to 20 weeks, with the dexfenfluramine dosage being 15 mg twice daily. Weight loss ranged from 2 to 23 pounds. None of the patients had any evidence of primary pulmonary hypertension or serotonin syndrome, despite being on serotonergic agents such as fluoxetine, paroxetine, and sertraline.

Citations

Aug 24, 2007·Expert Opinion on Investigational Drugs·Russell T Joffe

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