PMID: 9160280Apr 1, 1997Paper

Dextroamphetamine as a treatment for depression and low energy in AIDS patients: a pilot study

Journal of Psychosomatic Research
G J WagnerR Rabkin

Abstract

This report documents findings from an open trial of dextroamphetamine in the treatment of depression and low energy in AIDS patients. Dextroamphetamine offers the potential for rapid onset of effect and activation properties, both of which are important to persons with late stage HIV illness. Primary inclusion criteria included having a DSM-III-R depressive disorder, debilitating low energy, CD4 cell count below 200 cells/mm3, and no history of drug dependence. The trial consisted of open treatment in a 6-week protocol, with indefinite follow-up. Twenty-four men entered the study, 18 of 19 (95%) patients who completed at least 6 weeks of treatment reported substantial improvement with regard to both mood and energy at a median dosage of 10 mg/day. These results suggest that dextroamphetamine is a potentially effective, fast acting antidepressant treatment for this population and call for a larger, controlled trial.

References

Aug 1, 1988·Archives of General Psychiatry·J B Williams
Jan 1, 1995·International Journal of Psychiatry in Medicine·V F Holmes
Jan 1, 1995·Haemophilia : the Official Journal of the World Federation of Hemophilia·K K Hampton

❮ Previous
Next ❯

Citations

Jan 5, 2001·European Child & Adolescent Psychiatry·P J Santosh, E Taylor
Jul 26, 2008·Current Psychiatry Reports·Tami D Benton
May 17, 2005·Neuroscience and Biobehavioral Reviews·Alasdair M Barr, Athina Markou
Apr 6, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Alex ThompsonGlenn Treisman
Apr 9, 2001·Journal of Palliative Medicine·J Pereira, E Bruera
Jun 27, 2009·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Nancy R Reynolds
Nov 3, 2004·Journal of Psychosomatic Research·L J FulkG A Hand
Jun 5, 2001·The Journal of the Association of Nurses in AIDS Care : JANAC·J BormannA L Gifford
Feb 7, 2002·The Journal of the Association of Nurses in AIDS Care : JANAC·Julie Barroso, Mary R Lynn
Aug 9, 2005·Biological Psychiatry·Dwight L EvansWilliam J Valvo
Jul 13, 2005·Pediatric Clinics of North America·Tammy KangChris Feudtner
Aug 2, 2003·Biological Psychiatry·Dean G CruessJohn M Petitto
Jun 4, 2008·Psychosomatic Medicine·Martin J Repetto, John M Petitto
Sep 24, 1999·The Journal of the Association of Nurses in AIDS Care : JANAC·J Barroso
Aug 27, 2005·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Andrew A Pieper, Glenn J Treisman
Apr 23, 2016·Journal of Circadian Rhythms·Shawn D YoungstedtTeresa A Moore
Dec 4, 2012·Sleep·Laura K BargerShantha M W Rajaratnam
Sep 5, 2013·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Nicole Edgar, Colleen A McClung
Dec 10, 2015·Nutrition Research Reviews·Fiona M NeaClare A Corish
Sep 4, 1999·Journal of Clinical Pharmacy and Therapeutics·G M PetersonS Wilkinson
May 31, 2015·The Cochrane Database of Systematic Reviews·Martin MückeLukas Radbruch
Jun 15, 2010·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Dominique ElieAnik Giguère

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.