Diabetes and cardiovascular risk factors: the Framingham study

Circulation
W B Kannel, D L McGee

Abstract

The impact of cardiovascular disease was compared in non-diabetics and diabetics in the Framingham cohort. In the first 20 years of the study about 6% of the women and 8% of the men were diagnosed as diabetics. The incidence of cardiovascular disease among diabetic men was twice that among non-diabetic men. Among diabetic women the incidence of cardiovascular disease was three times that among non-diabetic women. Judging from a comparison of standardized coefficients for the regression of incidence of cardiovascular disease on specified risk factors, there is no indication that the relationship of risk factors to the subsequent development of cardiovascular disease is different for diabetics and non-diabetics. This study suggests that the role of diabetes as a cardiovascular risk factor does not derive from an altered ability to contend with known risk factors.

Citations

Feb 1, 1990·Diabetes/metabolism Reviews·F L Dunn
Jun 1, 1995·Diabetologia·C PailloleP Passa
Dec 1, 1988·Molecular and Cellular Biochemistry·D V GodinA D Goumeniouk
Apr 1, 1983·Acta diabetologica latina·A D HarrowerR Railton
Oct 3, 2007·Diabetologia·UNKNOWN Asia Pacific Cohort Studies Collaboration
Oct 12, 2012·Diabetologia·K A M Jandeleit-Dahm, S P Gray
Sep 17, 2009·Der Orthopäde·J F Zander, A Risse
Apr 7, 2006·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·A H LauruschkatJ Ennker
Apr 4, 2009·Wiener medizinische Wochenschrift·Michael ReslMartin Clodi
Mar 17, 2007·Heart Failure Reviews·V Melih AltanA Tanju Ozcelikay
Mar 2, 2010·Reviews in Endocrine & Metabolic Disorders·Miguel A ArizaJames L Rosenzweig
Sep 16, 2010·International Urology and Nephrology·Theodoros EleftheriadisGrammati Galaktidou
Oct 26, 2013·Current Atherosclerosis Reports·Xinghui SunMark W Feinberg
Mar 20, 2003·Current Diabetes Reports·Lawrence H YoungDeborah Chyun
Jun 3, 2005·Current Diabetes Reports·Moro O SalifuSamy I McFarlane
Apr 29, 2010·Current Diabetes Reports·Ayotunde O Dokun
Sep 2, 2003·Current Hypertension Reports·Gozewÿn LavermanGiuseppe Remuzzi
May 26, 2005·Current Hypertension Reports·Paolo VerdecchiaRoberto Gattobigio
Mar 28, 2008·Current Neurology and Neuroscience Reports·Karen Furie, Silvio E Inzucchi
May 31, 1991·Clinica Chimica Acta; International Journal of Clinical Chemistry·N IgakiM Kasuga
Jun 6, 1995·European Journal of Pharmacology·Y HattoriM Kanno

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