Diabetes, Dementia and Hypoglycemia

Canadian Journal of Diabetes
Graydon S Meneilly, Daniel M Tessier

Abstract

We are experiencing an epidemic of both diabetes and dementia among older adults in this country. The risk for dementia appears to be increased in patients with diabetes, and patients with dementia and diabetes appear to be at greater risk for severe hypoglycemia. In addition, there may be an increased risk for developing dementia by older patients with diabetes who have had episodes of severe hypoglycemia, although this issue is controversial. In this article, we review the factors that contribute to the increased risk for dementia in older adults with diabetes and outline the complex relationships between hypoglycemia and dementia.

References

Dec 20, 2005·Lancet Neurology·Geert Jan BiesselsPhilip Scheltens
May 4, 2007·The New England Journal of Medicine·Alan M JacobsonJudith Harth
Jun 10, 2008·The New England Journal of Medicine·Anushka PatelFlorence Travert
Jul 1, 2008·Journal of the American Medical Directors Association·Sheri R ColbergScott R Sechrist
Apr 16, 2009·JAMA : the Journal of the American Medical Association·Rachel A WhitmerJoseph V Selby
Apr 20, 2010·Journal of the American Geriatrics Society·Santosh B MurthyPaul E Schulz
Jan 12, 2011·Diabetic Medicine : a Journal of the British Diabetic Association·M W J Strachan
Jan 26, 2011·Nature Reviews. Endocrinology·Mark W J StrachanJacqueline F Price
Oct 26, 2011·Diabetic Medicine : a Journal of the British Diabetic Association·P P AungUNKNOWN Edinburgh Type 2 Diabetes Study Investigators
Dec 14, 2011·Journal of the American Geriatrics Society·Denise G FeilLeonard M Pogach
Apr 24, 2012·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Michael L JohnsonRobert O Morgan
Sep 26, 2012·Journal of Internal Medicine·C-H Lin, W H-H Sheu
Oct 27, 2012·Diabetes Care·M Sue KirkmanCarrie S Swift
Jun 12, 2013·JAMA Internal Medicine·Kristine YaffeUNKNOWN Health ABC Study
May 16, 2014·Canadian Journal of Diabetes·Graydon S MeneillyDaniel Tessier
Oct 10, 2013·Diabetes Care·Insa FeinkohlUNKNOWN Edinburgh Type 2 Diabetes Study (ET2DS) Investigators
Dec 18, 2013·Diabetes/metabolism Research and Reviews·Tali Cukierman-Yaffe
Mar 14, 2014·The Lancet. Diabetes & Endocrinology·Lieza G ExaltoRachel A Whitmer
Mar 14, 2014·The Lancet. Diabetes & Endocrinology·Geert Jan BiesselsRachel A Whitmer
Mar 14, 2014·Current Diabetes Reports·Toshiharu Ninomiya
Aug 19, 2014·Diabetic Medicine : a Journal of the British Diabetic Association·A J SinclairUNKNOWN National Expert Working Group
Dec 3, 2014·Clinics in Geriatric Medicine·Elizabeth Rose MayedaKristine Yaffe
Dec 17, 2014·World Journal of Diabetes·Mario Barbagallo, Ligia J Dominguez
Jan 13, 2015·Diabetes·Auriel A WilletteUNKNOWN Alzheimer’s Disease Neuroimaging Initiative
Feb 26, 2015·Diabetes·Antje Gottschalk, Björn Ellger
Jun 23, 2015·Journal of the American Geriatrics Society·Katherine J BangenJosé A Luchsinger

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Citations

Oct 7, 2016·Drugs & Aging·Jelena Osmanovic-Barilar, Melita Salkovic-Petrisi
Apr 6, 2017·Journal of Diabetes Science and Technology·Michelle L Litchman, Nancy A Allen
Oct 13, 2018·Metabolic Syndrome and Related Disorders·Michael Palacios-MendozaRocio Santibanez
Nov 21, 2019·Journal of the American Geriatrics Society·Courtney A PolenickHelen C Kales
Feb 29, 2020·Journal of Neurology, Neurosurgery, and Psychiatry·Valentina GalloDamien McElvenny
Aug 14, 2020·Pflügers Archiv : European journal of physiology·Hermann Koepsell
Apr 14, 2019·International Journal of Environmental Research and Public Health·Li ZhangZhaofeng Zhang
Mar 28, 2020·Nature Communications·Louis-Philippe BernierBrian A MacVicar
Apr 1, 2020·F1000Research·Steven A Rosenzweig
Jan 9, 2021·BMC Geriatrics·Monica HermannMarit Graue
Apr 16, 2021·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Zhi-Miao ZhangJin-Ao Duan
Jun 1, 2021·Journal of Alzheimer's Disease : JAD·Rafia S RasuSid E O'Bryant
Sep 10, 2019·Chemico-biological Interactions·Maria Rosa Trentin ZorzenonCecília Edna Mareze-Costa
Aug 30, 2019·Diabetes Spectrum : a Publication of the American Diabetes Association·Michelle L LitchmanCynthia A Berg

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