Abstract
The classification of diabetes mellitus by types (1 or 2), or by age of onset (juvenile or adult), helps to clarify many aspects of pathophysiology, prognosis, and therapy. However, less-commonly encountered patients, presenting in childhood or adolescence, may not fit neatly into one or the other group. These include teenagers who present with new-onset diabetes with ketoacidosis, but who are later able to be managed permanently as type 2 patients. Other adolescent patients present with only minimal glucose intolerance, then proceed to develop type 1 diabetes, with evidence of autoimmune etiology, after a variable number of years. Four patients are presented to illustrate these diagnostic dilemmas.
References
Apr 1, 1976·The New England Journal of Medicine·C R KahnJ Roth
Nov 1, 1992·Diabetes·S I Taylor
Nov 1, 1989·Diabetes/metabolism Reviews·S S Fajans
Mar 1, 1988·Diabetologia·G FarmerH W Sutherland
Jan 1, 1986·Diabetes Care·C NaidooS M Joubert
Jul 1, 1984·Diabetic Medicine : a Journal of the British Diabetic Association·T J LyonsJ A Weaver
Mar 1, 1984·The Journal of Clinical Investigation·D C RobbinsH S Tager
Sep 6, 1984·The New England Journal of Medicine·P A GruppusoR Schwartz
Jul 1, 1982·Diabetes Care·J A ScarlettO G Kolterman
Jan 1, 1981·Acta Medica Scandinavica·S MadsbadC Binder
May 1, 1981·Diabetes Care·M RendellD Ross
Dec 1, 1993·Cell Adhesion and Communication·M Enomoto-IwamotoD Boettiger
Jul 1, 1995·Diabetes Care·P Z Zimmet
Apr 1, 1995·Diabetic Medicine : a Journal of the British Diabetic Association·C S YajnikD J Barker
Oct 1, 1993·Journal of Diabetes and Its Complications·J S SkylerV Byers
Feb 1, 1995·Human Genetics·A CamaS I Taylor
Apr 1, 1994·Diabetic Medicine : a Journal of the British Diabetic Association·P Z ZimmetD A Lang
May 1, 1993·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·D G Albertson, J N Thomson
Jun 1, 1994·Diabetes·M A BanerjiH E Lebovitz
Jun 1, 1993·Diabetes Care·A GottsäterG Sundkvist
Sep 1, 1993·Diabetes Care·S S Fajans, M B Brown
Feb 1, 1993·Diabetes·T TuomiI R Mackay
May 1, 1993·Diabetes·J S Skyler
Feb 1, 1996·Diabetes·F M Matschinsky
Mar 1, 1996·Diabetes·M A BanerjiH E Lebovitz
Aug 1, 1997·Diabetes Care·S C ElbeinG Eisenbarth
Dec 10, 1997·Diabetes·P BoutinP Froguel
Apr 17, 1998·Diabetic Medicine : a Journal of the British Diabetic Association·C H FallC N Hales
May 6, 1999·The New England Journal of Medicine·O Pinhas-Hamiel, P Zeitler
May 20, 1999·Diabetes Care·A L RosenbloomW E Winter