PMID: 12603213Feb 27, 2003Paper

Diabetes mellitus after kidney transplantation in the United States

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Bertram L KasiskeArthur J Matas

Abstract

New onset diabetes is a major complication after kidney transplantation. However, the incidence, risk factors and clinical relevance of post-transplant diabetes mellitus (PTDM) vary among reports from single-center observational studies and clinical trials. Using data from the United Renal Data System we identified 11 659 Medicare beneficiaries who received their first kidney transplant in 1996-2000. The cumulative incidence of PTDM was 9.1% (95% confidence interval = 8.6-9.7%), 16.0% (15.3-16.7%), and 24.0% (23.1-24.9%) at 3, 12, and 36 months post-transplant, respectively. Using Cox's proportional hazards analysis, risk factors for PTDM included age, African American race (relative risk = 1.68, range: 1.52-1.85, p < 0.0001), Hispanic ethnicity (1.35, range: 1.19-1.54, p < 0.0001), male donor (1.12, range: 1.03-1.21, p = 0.0090), increasing HLA mismatches, hepatitis C infection (1.33, range: 1.15-1.55, p < 0.0001), body mass index >or=30 kg/m2 (1.73, range: 1.57-1.90, p < 0.0001), and the use of tacrolimus as the initial maintenance immunosuppressive medication (1.53, range: 1.29-1.81, p < 0.0001). Factors that reduced the risk for PTDM included the use of mycophenolate mofetil, azathioprine, younger recipient age, glomerulone...Continue Reading

References

Jan 1, 1990·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·A von KiparskiU Binswanger
Jul 1, 1988·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·N YoshimuraT Oka
Jan 1, 1985·American Journal of Nephrology·E A FriedmanK M Butt
May 1, 1996·Journal of the American Society of Nephrology : JASN·C PonticelliL Belli
Mar 11, 1998·Journal of Clinical Gastroenterology·H KnoblerS H Roman
Jan 27, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A L MasonR P Perrillo
Jan 7, 2000·American Journal of Medical Quality : the Official Journal of the American College of Medical Quality·P L HebertA M McBean
Jun 28, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D L BigamM S Cattral
Dec 20, 2000·Transplantation Proceedings·F Jawad, S A Rizvi
Feb 8, 2002·The New England Journal of Medicine·William C KnowlerUNKNOWN Diabetes Prevention Program Research Group

❮ Previous
Next ❯

Citations

Sep 16, 2004·Transplant International : Official Journal of the European Society for Organ Transplantation·Marcus D SäemannGerhard J Zlabinger
Nov 2, 2004·Transplant International : Official Journal of the European Society for Organ Transplantation·Karen L HardingerMark A Schnitzler
Apr 7, 2006·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·M LoebeD J Hamilton
May 15, 2008·Langenbeck's Archives of Surgery·Michael NeippJürgen Klempnauer
Jun 15, 2006·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Katalin DittrichJörg Dötsch
Jun 28, 2005·Clinical and Experimental Nephrology·Ralf SchielGünter Stein
Sep 17, 2009·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Maristela BohlkeRicardo Sesso
Oct 12, 2012·International Urology and Nephrology·Erhan TatarHuseyin Toz
Apr 28, 2010·Journal of General Internal Medicine·Gaurav GuptaPeggy B Hasley
Jun 3, 2005·Current Diabetes Reports·Moro O SalifuSamy I McFarlane
Jul 22, 2005·Current Diabetes Reports·Boaz Hirshberg
Jul 22, 2005·Current Diabetes Reports·Martha Pavlakis
Jul 16, 2008·Current Diabetes Reports·Moro O SalifuSamy I McFarlane
Jul 18, 2008·Current Diabetes Reports·Elizabeth Diakoff
Jul 31, 2009·Current Diabetes Reports·Vittoria BonatoMario Carmellini
Aug 9, 2012·Current Diabetes Reports·Giselle GuerraGaetano Ciancio
Mar 14, 2013·Current Hypertension Reports·Heather LaGuardia, Rubin Zhang
Jun 1, 2010·The Indian Journal of Surgery·Koosha KamaliMohammad Hasan Seifee
Aug 31, 2006·Nature Clinical Practice. Nephrology·Claudio Rigatto, Patrick Parfrey
Oct 18, 2007·Nature Clinical Practice. Nephrology·Richard Moore
Aug 30, 2008·Nature Clinical Practice. Nephrology·David Philibert, Daniel Cattran
Sep 8, 2010·The New England Journal of Medicine·Krista L LentineDaniel C Brennan
Dec 24, 2004·The New England Journal of Medicine·Mohamed H Sayegh, Charles B Carpenter
Dec 24, 2004·The New England Journal of Medicine·Philip F Halloran
May 5, 2010·Proceedings of the National Academy of Sciences of the United States of America·Graham M WestMichael C Fitzgerald
Oct 15, 2010·The Journal of Biological Chemistry·Scott A SoleimanpourDoris A Stoffers
Jan 31, 2007·The Journal of Infectious Diseases·Nina SinghUNKNOWN Cryptococcal Collaborative Transplant Study Group
Apr 29, 2005·Diabetes Technology & Therapeutics·Jack PollardJacques Pappo
Mar 29, 2008·Metabolic Syndrome and Related Disorders·Agnes Lo
Oct 21, 2010·Metabolic Syndrome and Related Disorders·Magdalene SzuszkiewiczNicola Abate
Dec 3, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Claudio Ponticelli
Feb 11, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Alev AtaseverAbdullah Sayiner
Mar 3, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Bernhard K KrämerUNKNOWN European Tacrolimus vs Cyclosporin Microemulsion Renal Transplantation Study Group
May 10, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Hoi Wong ChanChun Sang Li
Oct 15, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Fu Liang NgIain A M Macphee
Nov 26, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Willy AasebøHallvard Holdaas
Sep 21, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Katarzyna MadziarskaMarian Klinger
Apr 8, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Karsten MidtvedtAnders Åsberg
May 28, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Kathleen ClaesHenrik Ekberg
Jan 19, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Manfred HeckingUNKNOWN European-New-Onset Diabetes After Transplantation Working Group
Oct 16, 2004·Current Opinion in Nephrology and Hypertension·Y Mun WooJohn S Gill

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Robert S WoodwardDaniel C Brennan
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Olaf HeiselPaul Keown
© 2021 Meta ULC. All rights reserved