PMID: 3963328Mar 1, 1986

Diabetes mellitus and open heart surgery. A simple, practical closed-loop insulin infusion system for blood glucose control

B G WatsonM Williamson


A method, based on bedside determinations of blood glucose by nursing staff, was designed to control the administration of insulin to diabetic patients during and following open heart surgery. A computer-controlled intravenous infusion pump was used to deliver the insulin. Excellent control of the hyperglycaemia normally associated with open heart surgery was achieved, with 84 percent of measured blood glucose values falling within 2 mmol/litre of the target value of 6 mmol/litre. The method proved to be simple, effective, and safe.


Jun 1, 1985·British Journal of Anaesthesia·C K McKnightM P Holden
Mar 1, 1981·The British Journal of Surgery·G V GillK G Alberti


Jan 1, 1988·Diabetic Medicine : a Journal of the British Diabetic Association·P A CrockJ D Best
Sep 16, 2017·Current Diabetes Reports·Carlos E Mendez, Guillermo E Umpierrez
Oct 1, 1995·Medical Informatics = Médecine Et Informatique·E D Lehmann, T Deutsch
Mar 1, 1995·Journal of General Internal Medicine·R L Schiff, M A Emanuele
Mar 19, 2002·International Anesthesiology Clinics·Silvio E Inzucchi
Feb 1, 1991·Diabetic Medicine : a Journal of the British Diabetic Association·B G WatsonD A Pay
Feb 11, 2010·Journal of Diabetes Science and Technology·Jeffrey I JosephZvi Grunwald

Related Concepts

Blood Glucose
Diabetes Mellitus
Cardiac Surgery Procedures
Implantable Programmable Insulin Pump
Intraoperative Period
Personal Computers
Postoperative Period

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