Diabetes Mellitus-Associated Uveitis: Clinical Features in a Chilean Series.

Ocular Immunology and Inflammation
Pablo E SabatVíctor Velásquez

Abstract

To describe clinical features of patients with diabetes mellitus-associated uveitis (DMAU). Retrospective analysis of clinical records of patients with uveitis and diabetes mellitus (DM) presented in an uveitis referral centre in Chile. Demographic data, comorbidities, complete ophthalmic examination, and treatments were analyzed. We found 72 patients with uveitis and DM: 16 with DMAU and poorly regulated DM (22%), 15 with DMAU and well-controlled DM (21%), and 41 with uveitis due to established other causes than DM (57%). Patients with DMAU in poorly regulated diabetes, presented inflammation of 3-4+ cells in 33%, a fibrinous reaction in 28%, hypopyon in 17% and posterior synechiae in 83%, compared with 5%, 0%, 0%, and 50% in the group with well-controlled DM, respectively (p < 0.05). Most DMAU patients responded well to topical or periocular steroids. Patients with DMAU with poorly regulated DM present a more severe inflammation compared with patients with DMAU with well-controlled DM.

References

Jul 15, 1988·American Journal of Ophthalmology·A RothovaA Kijlstra
Jan 1, 1995·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·I CastagnaG Salmeri
Sep 1, 1996·The British Journal of Ophthalmology·M S Suttorp-Schulten, A Rothova
Oct 1, 2005·American Journal of Ophthalmology·Douglas A JabsUNKNOWN Standardization of Uveitis Nomenclature (SUN) Working Group
Dec 17, 2009·Ocular Immunology and Inflammation·Kadambari S OswalPhilip I Murray
Aug 21, 2013·Seminars in Ophthalmology·Manish Kumar SinhaJay Kumar Chhablani
Mar 23, 2018·The British Journal of Ophthalmology·Takayo WatanabeAnnabelle A Okada

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