Diabetes mellitus in a population of 180,000 insured dogs: incidence, survival, and breed distribution

Journal of Veterinary Internal Medicine
T FallAgneta Egenvall

Abstract

Canine diabetes mellitus (DM) is a common endocrinopathy with an unclear etiology. For a better understanding of the underlying mechanisms, there is a need for comprehensive epidemiologic studies. Earlier studies have shown that the risk of disease is higher in certain dog breeds. Incidence, age of onset, survival and sex proportion of DM vary by breed. Data from a cohort of 182,087 insured dogs aged 5-12 years accounting for 652,898 dog-years at risk were studied retrospectively. Incidence rates by sex, breed, and geography were calculated with exact denominators. Age-specific incidence and survival after 1st DM claim were computed with Cox's regression and Kaplan-Meier survival function. Multivariable survival analysis was performed for the outcome diagnosis of DM with age, sex, and geography tested as fixed effects, previous endocrine or pancreatic diseases tested as time-dependent covariates, and breed tested as a random effect. The mean age at 1st insurance claim for the 860 DM dogs (72% females) was 8.6 years. The incidence of DM was 13 cases per 10,000 dog-years at risk. Australian Terriers, Samoyeds, Swedish Elkhounds, and Swedish Lapphunds were found to have the highest incidence. The proportion of females with DM vari...Continue Reading

Citations

Nov 9, 2010·Journal of Veterinary Internal Medicine·T FallO Kämpe
Oct 31, 2009·Acta Veterinaria Scandinavica·Agneta EgenvallBrenda N Bonnett
Dec 3, 2009·The Journal of Veterinary Medical Science·Hirokazu IshinoMasahiro Tagawa
Feb 5, 2013·Domestic Animal Endocrinology·D J BatchelorS P Shirazi-Beechey
May 5, 2011·The Journal of Small Animal Practice·A-K WejdmarkT Fall
Jun 10, 2014·Veterinary Surgery : VS·Daniela VrabelovaAmer Rajab
Jan 15, 2015·The Journal of Small Animal Practice·L J Davison
May 6, 2015·The Veterinary Record·L PelanderJ Häggström
Jun 2, 2016·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Yeray Brito-CasillasAna María Wägner
Apr 8, 2017·Veterinary Clinical Pathology·Anne F GoemansIan K Ramsey

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