Diabetes mellitus/male infertility

Archives of Andrology
D Dinulovic, G Radonjic


Diabetes mellitus (DM), associated with very subtle disorders, affects, either directly or indirectly, various functions of the reproductive system. Adequate, regular, and timely therapy may prevent or delay these disorders. The T synthesis disorder is caused by molecular changes at the level of Leydig cells and may lead to other disorders in all target organs and tissues. The close correlation between Leydig and Sertoli cells function, i.e., between spermatogenesis and second sex glands function, results in certain anomalies in diabetic patients' spermiograms. Parallel lesions associated with DM, through CNS (hypothalamus-hypophysis), and endocrine profile are indirectly intensified or induced by these disorders, which reflect dysfunction of homeostatic balance in carbohydrate metabolism. Sexual dysfunction in all its forms (reduced erection, impotence, and other libido dissociations) is an accompanying phenomenon of the diabetic disease. However, manifestations of these disorders are related to the regulation of carbohydrate metabolism and to the duration of disease. The duration of disease is not necessarily correlated with sexual dysfunction. Even carbohydrate metabolism remains within normal range in addition to other lesi...Continue Reading


Feb 1, 1979·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·J C CalvoE H Charreau
Oct 1, 1977·The Journal of Clinical Endocrinology and Metabolism·J D RobinsonS S Yen
Dec 1, 1977·Diabetes·W E SzpunarD S McCann
Jul 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J H Dorrington, D T Armstrong
Aug 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·M L DufauK J Catt
Jan 1, 1979·Molecular and Cellular Endocrinology·F H de Jong
Dec 1, 1977·Fertility and Sterility·P F TauberL J Zaneveld
Feb 1, 1978·Biology of Reproduction·J H DorringtonD T Armstrong
Apr 1, 1977·Steroids·B SanbornE Steinberger
Sep 1, 1976·Endocrinology·A Steinberger, E Steinberger
Aug 1, 1976·The Journal of Endocrinology·E MulderH J van der Molen
Apr 1, 1976·The Journal of Endocrinology·M S Cameo, J A Blaquier
Jan 1, 1989·Annual Review of Pharmacology and Toxicology·H S Margolius
May 15, 1989·Diabetes Research and Clinical Practice·H FushimiY Okazaki
Mar 1, 1988·Diabetic Medicine : a Journal of the British Diabetic Association·C G SempleG H Beastall
Sep 1, 1988·Fertility and Sterility·M P DiamondA D Cherrington
Jul 1, 1987·The Journal of Clinical Endocrinology and Metabolism·F T MurrayA G Glaros
Jan 1, 1985·Postgraduate Medical Journal·A D MooradianR B Shafer
Sep 1, 1985·Andrologia·H Kaemmerer, H J Mitzkat
Jan 1, 1974·Basic Life Sciences·E SteinbergerB Sanborn
Apr 1, 1974·Diabetes·R C KolodnyD M Barnett
Mar 1, 1969·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·V G Foglia Cattaneo de Paralta Ram
Apr 1, 1982·Molecular and Cellular Endocrinology·R M Sharpe, I Cooper
Aug 1, 1984·British Journal of Obstetrics and Gynaecology·M E SaidI MacGillivray
Dec 23, 1982·Clinica Chimica Acta; International Journal of Clinical Chemistry·M AlasandroM Novotny
Feb 1, 1984·Journal of Endocrinological Investigation·S AndòR Rottiers
Jun 1, 1984·Clinical Endocrinology·H N CohenA C MacCuish
Mar 1, 1980·The Journal of Clinical Investigation·S B CigorragaM L Dufau
Mar 15, 1980·The Biochemical Journal·A F Karl, M D Griswold
Apr 30, 1981·Nature·R M SharpeF F Rommerts
Jun 1, 1983·Metabolism: Clinical and Experimental·G FederspilC Scandellari
Mar 1, 1984·Journal of Steroid Biochemistry·J C CalvoE H Charreau
Dec 1, 1983·The Journal of Clinical Endocrinology and Metabolism·F CamanniE E Müller
Jul 1, 1980·Cell Biology International Reports·A F Karl, M D Griswold
Aug 15, 1982·American Journal of Obstetrics and Gynecology·H DjursingL M Pedersen
Jun 15, 1982·The Biochemical Journal·G H BakkerH J van der Molen
Dec 1, 1960·American Journal of Diseases of Children·S G DRISCOLLG W CURTIS
Sep 1, 1964·Diabetes·S LOCKE
Nov 1, 1961·Acta Endocrinologica·E L HUNT, D W BAILEY
Jan 15, 1962·American Journal of Obstetrics and Gynecology·A RUBIN


Jan 5, 2007·Biological & Pharmaceutical Bulletin·Chhanda MallickDebidas Ghosh
May 15, 2012·Asian Journal of Andrology·Yagil BarazaniDoron S Stember
Sep 4, 2016·Human Reproduction·Michael L EisenbergGermaine M Buck Louis
Nov 14, 2003·Human Fertility : Journal of the British Fertility Society·David R J GlennSheena E M Lewis
Aug 5, 2004·Journal of Andrology·Joan BallesterJoan E Rodríguez-Gil
Oct 21, 2005·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Singh SoudamaniKarundevi Balasubramanian
Dec 21, 2006·The Journal of Reproduction and Development·Gholamali JelodarVahid Gholampour
Sep 18, 2009·Journal of Cellular Biochemistry·Soudamani SinghKarundevi Balasubramanian
Mar 1, 2006·Indian Journal of Clinical Biochemistry : IJCB·M ManeeshAmit Chakrabarti
Aug 2, 2019·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Prakash SeppanSathya Bharathy Sathyanathan
Oct 22, 2014·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Manuel NistalMiguel Reyes-Múgica
May 6, 2015·Chronobiology International·A De GiorgiF Fabbian
Nov 2, 2018·Current Medicinal Chemistry·R S TavaresSandra Amaral
Oct 30, 2003·Aging Clinical and Experimental Research·Gaetano Frajese, Flavio Pozzi
Nov 4, 2011·Systems Biology in Reproductive Medicine·Iraj AmiriMarziye Ghorbani
Apr 22, 2009·International Urology and Nephrology·Abdulbari BenerAbdulla O A A Al-Hamaq
Oct 7, 2020·AJR. American Journal of Roentgenology·William T HaddadValdair Francisco Muglia
May 18, 2016·Fertility and Sterility·Michael L EisenbergValerie L Baker

Related Concepts

Diabetes Mellitus
Microangiopathy, Diabetic
Subfertility, Male
Complications of Diabetes Mellitus

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