Diabetes-Multimorbidity Combinations and Disability Among Middle-aged and Older Adults

Journal of General Internal Medicine
Ana R QuiñonesAnda Botoseneanu

Abstract

Older adults with diabetes rarely have only one chronic disease. As a result, there is a need to re-conceptualize research and clinical practice to address the growing number of older Americans with diabetes and concurrent chronic diseases (diabetes-multimorbidity). To identify prevalent multimorbidity combinations and examine their association with poor functional status among a nationally representative sample of middle-aged and older adults with diabetes. A prospective cohort study of the 2012-2014 Health and Retirement Study (HRS) data. We identified the most prevalent diabetes-multimorbidity combinations and estimated negative binomial models of diabetes-multimorbidity on prospective disability. Analytic sample included 3841 HRS participants with diabetes, aged 51 years and older. The main outcome measure was the combined activities of daily living (ADL)-instrumental activities of daily living (IADL) index (range 0-11; higher index denotes higher disability). The main independent variables were diabetes-multimorbidity combination groups, defined as the co-occurrence of diabetes and at least one of six somatic chronic diseases (hypertension, cardiovascular disease, lung disease, cancer, arthritis, and stroke) and/or two men...Continue Reading

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Citations

Dec 12, 2020·PloS One·Shamini PrathapanBatheegama Gamarachchige Gayasha Kavindi Somathilake
Nov 14, 2020·Archives of Gerontology and Geriatrics·Sean P McClellanCarmen García-Peña
Dec 5, 2020·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Zyta Beata Wojszel, Lukasz Magnuszewski
Apr 22, 2021·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Anda BotoseneanuAna R Quiñones
Jun 27, 2021·Nature Reviews. Endocrinology·Srikanth BellaryClifford J Bailey

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