Diabetic foot infection in hospitalized adults

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
David E KatzDror Marchaim

Abstract

Acute infections of the diabetic foot (DFI) are a common and complex condition. Patients are generally managed in the ambulatory setting and epidemiological data pertaining to hospitalized patients is lacking. The aim of this study was to analyze the epidemiology, microbiology and outcomes of hospitalized patients with DFI, who are managed at a referral center equipped with hyperbaric oxygen (HBO) therapy. A retrospective cohort study of adult patients admitted to a tertiary referral center with DFI over a six-month period in 2013 was undertaken. Predictors of clinical outcomes and efficacy of treatment modalities were analyzed by Cox regression. Sixty-one patients with DFI were identified. Most patients were elderly (67 ± 13 years), with long-standing (17 ± 9 years), poorly controlled (HbA1c 9 ± 3%) diabetes. Most patients had polymicrobial infection (80%); specifically, anaerobic (39%) and multi or extensively-drug resistant organisms (61%). Administration of appropriate antimicrobials was delayed for >48 h in 83%. Advanced age was associated with worse outcomes. Sicker patients with severe peripheral vascular disease were managed with HBO. The use of HBO was associated with higher costs and increased functional deterioration...Continue Reading

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Citations

May 1, 2019·The International Journal of Lower Extremity Wounds·José Miguel NevesJosé Neves
Mar 21, 2020·International Wound Journal·Pinar Sen, Tuna Demirdal
Aug 30, 2020·BMC Endocrine Disorders·Olufunmilayo O AdeleyeMarcelina Enamino
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Dec 10, 2020·International Journal of General Medicine·Khanda AnwarJamal Salih
Nov 19, 2018·The American Journal of the Medical Sciences·Natalia Malachowa, Frank R DeLeo

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