Diabetic Foot Infections: The Diagnostic Challenges

Journal of Clinical Medicine
Chiara LauriLuigi Uccioli

Abstract

Diabetic foot infections (DFIs) are severe complications of long-standing diabetes, and they represent a diagnostic challenge, since the differentiation between osteomyelitis (OM), soft tissue infection (STI), and Charcot's osteoarthropathy is very difficult to achieve. Nevertheless, such differential diagnosis is mandatory in order to plan the most appropriate treatment for the patient. The isolation of the pathogen from bone or soft tissues is still the gold standard for diagnosis; however, it would be desirable to have a non-invasive test that is able to detect, localize, and evaluate the extent of the infection with high accuracy. A multidisciplinary approach is the key for the correct management of diabetic patients dealing with infective complications, but at the moment, no definite diagnostic flow charts still exist. This review aims at providing an overview on multimodality imaging for the diagnosis of DFI and to address evidence-based answers to the clinicians when they appeal to radiologists or nuclear medicine (NM) physicians for studying their patients.

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Citations

Aug 1, 2020·Medicina·Bogdan UivaraseanuDana Carmen Zaha
Mar 9, 2021·Journal of Clinical Orthopaedics and Trauma·Karthikeyan P IyengarSobhan Vinjamuri
Jun 8, 2021·Clinical and Translational Imaging : Reviews in Nuclear Medicine and Molecular Imaging·Alberto SignoreChiara Lauri
Jul 20, 2021·Clinical and Translational Imaging : Reviews in Nuclear Medicine and Molecular Imaging·Massimiliano CasaliAlberto Signore
Dec 20, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Yang FuXinwang Yang

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Methods Mentioned

BETA
amputation
amputations
biopsy
ESR
imaging techniques

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