PMID: 2509623Oct 1, 1989Paper

Diabetic ketoacidosis in Denmark: epidemiology, incidence rates, precipitating factors and mortality rates

Journal of Internal Medicine
O SnorgaardJ Nerup

Abstract

The epidemiology of uncontrolled diabetes mellitus was studied in an 11.2% sample of the Danish population (574,696 inhabitants) during a 24-month period. Some 175 admissions in ketoacidosis (heavy ketonuria and plasma bicarbonate below 21 mmol/l) were recorded. Based on prevalence rates from a socio-economically and ethnically comparable Danish county, the annual incidence rate was calculated to be 0.045 per diabetic. The incidence rate of moderate and severe episodes (bicarbonate less than 16 mmol/l) was 0.032 and of severe episodes only (bicarbonate less than 10 mmol/l) 0.017 per diabetic. The major risk group was female teenagers. The total annual frequency of recurrence was 8.7%: 48% of the male episodes were ketoacidosis (DKA) associated with onset of diabetes, against 30% of the female episodes (P = 0.02). All Danish diabetics were at the time of the survey (1978-79) treated with conventional insulin treatment. Annual incidence rate in these established diabetics was 0.028, i.e. three to five times less than reported during treatment with continuous subcutaneous insulin infusion. Mortality of DKA was low, 3.4%, and dependent upon age and precipitating factor but not upon the degree of acidosis. The overall annual mortali...Continue Reading

References

Oct 1, 1977·Archives of Internal Medicine·K G Alberti
May 1, 1977·Acta diabetologica latina·P SingerV Schliack
May 1, 1987·Diabetic Medicine : a Journal of the British Diabetic Association·K Borch-JohnsenJ Nerup
Dec 1, 1988·Diabetic Medicine : a Journal of the British Diabetic Association·H B MortensenK E Petersen
May 5, 1973·Lancet·N G SolerJ M Malins
May 1, 1984·Diabetic Medicine : a Journal of the British Diabetic Association·P D Home, S M Marshall
May 1, 1983·American Journal of Epidemiology·G A FaichS E Ellis
Jul 1, 1981·Diabetologia·E A GaleR B Tattersall
Mar 1, 1982·Diabetes Care·M C Sheppard, A D Wright
Aug 26, 1982·The New England Journal of Medicine·R S MecklenburgW J Steenrod

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Citations

Jun 7, 1996·Biochimica Et Biophysica Acta·K MatsudaN Tamaki
Jul 1, 1995·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·J C Surís
Mar 1, 1997·Diabetes Research and Clinical Practice·M al KhawariM A Moussa
Mar 16, 2004·Pediatric Diabetes·Thao P BuiFergus J Cameron
Mar 11, 1999·Acta Physiologica Scandinavica·H B Nielsen
May 23, 2000·Diabetic Medicine : a Journal of the British Diabetic Association·J OstmanL Wibell
Sep 13, 2001·Diabetic Medicine : a Journal of the British Diabetic Association·T M WallaceD R Matthews
Nov 27, 2002·Diabetes Technology & Therapeutics·Ulf Samuelsson, Johnny Ludvigsson
May 1, 1995·Diabetic Medicine : a Journal of the British Diabetic Association·C J ThompsonR W Newton
May 7, 1994·BMJ : British Medical Journal·J H Christensen, J M Møller
May 13, 2004·Postgraduate Medical Journal·P English, G Williams
Sep 5, 2003·Postgraduate Medical Journal·D KamalakannanT A M Abdu
Apr 17, 2008·The American Journal of the Medical Sciences·Fernando OvalleBarbara Gower
Jan 1, 1992·Baillière's Clinical Endocrinology and Metabolism·W Berger, U Keller
Jan 22, 2005·Diabetic Medicine : a Journal of the British Diabetic Association·S HarrisR Hillson
Aug 4, 2007·Diabetic Medicine : a Journal of the British Diabetic Association·R HanasB Lindblad
Jan 1, 2005·Biosensors & Bioelectronics·Nigel J ForrowJared L Watkin
Sep 9, 2006·Diabetes Research and Clinical Practice·Otto M HenriksenOle Lander Svendsen
Feb 7, 2006·Diabetes Research and Clinical Practice·Stephanie T ChungMichael S Boyne
Nov 1, 1992·Journal of the American Geriatrics Society·M L MaloneJ S Goodwin
Jan 9, 2001·Accident and Emergency Nursing·R Lewis
Apr 16, 2016·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Yehuda HandelsmanMatthew R Weir
Feb 6, 2013·Diabetes Research and Clinical Practice·G O AbdulrahmanO E Okosieme
Nov 20, 1998·Acta Paediatrica. Supplement·D Daneman, M Frank
Jul 1, 1999·Clinics in Chest Medicine·F J Martinez, R W Lash

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