Diabetic macular morphology changes may occur in the early stage of diabetes

BMC Ophthalmology
Yanwei ChenXi Shen

Abstract

The purpose of this study was to observe whether invisible morphological changes are presented in the two types of diabetes mellitus patients without diabetic retinopathy. Twenty-six type 1 diabetes mellitus (T1DM) patients and 34 type 2 diabetes mellitus (T2DM) patients without diabetic retinopathy (DR) were recruited for this study. They underwent complete examinations that included stereoscopic color fundus photography and optical coherence tomography (OCT). The OCT patterns were used to measure the macular retinal thickness (RT), the ganglion cell and inner plexiform layer (GC-IPL) complex thickness, the inner nuclear layer (INL) thickness, the outer nuclear layer (ONL) thickness and the subfoveal choroidal thickness (SFCT) using the enhanced depth imaging (EDI) patterns and the retinal fiber layer (RNFL) thickness around the optic disc. All results were compared to those of age- and sex-matched control groups. In the patients with T1DM, the mean RT and GC-IPL complex thicknesses were significantly thinner than those of the control group (p < 0.05). The RNFL was found to be thinner at the 9 o'clock position around the optic disc in the patients compared with the control group. The SFCTs were similar in the controls and subj...Continue Reading

References

Nov 1, 1975·The British Journal of Ophthalmology·J Cunha-VazA J Campos
Oct 23, 2002·Acta Ophthalmologica Scandinavica·Thomas A CiullaBruce Martin
Mar 27, 2003·Progress in Neuro-psychopharmacology & Biological Psychiatry·Alistair J Barber
Apr 14, 2004·Archives of Ophthalmology·Monique S RoyJohn H Kempen
Apr 14, 2004·Archives of Ophthalmology·John H KempenUNKNOWN Eye Diseases Prevalence Research Group
Aug 25, 2004·Investigative Ophthalmology & Visual Science·Pamela M MartinSylvia B Smith
Nov 22, 2005·The British Journal of Ophthalmology·A Lecleire-ColletS Picaud
Jul 8, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Xi Wei XieJost B Jonas
Jan 20, 2009·Investigative Ophthalmology & Visual Science·Hille W van DijkMichael D Abràmoff
Jan 27, 2009·Ophthalmology·Feng Hua WangTien Yin Wong
Feb 5, 2010·Investigative Ophthalmology & Visual Science·Hille W van DijkMichael D Abràmoff
Jan 11, 2011·The British Journal of Ophthalmology·Hae Young-Lopilly ParkChan Kee Park
May 4, 2011·World Journal of Diabetes·Marta VillarroelRafael Simó
Mar 30, 2012·The New England Journal of Medicine·David A AntonettiThomas W Gardner
Aug 11, 2012·Investigative Ophthalmology & Visual Science·Giuseppe QuerquesFrancesco Bandello
Apr 26, 2013·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Isabel PiresConceição Lobo
Apr 8, 2014·Clinical Ophthalmology·Erkan UnsalHülya Güngel

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Citations

May 23, 2016·Journal of Diabetes and Its Complications·Kazuki HashimotoToru Nakazawa
Mar 1, 2018·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Kemal TekinZehra Aycan
Apr 24, 2018·Journal of Diabetes Research·Jing JiangXiaofang Xu
Jun 7, 2020·Journal of Clinical Medicine·Jacqueline ChuaLeopold Schmetterer
Sep 17, 2020·Visual Neuroscience·Erika D Eggers, Teresia A Carreon
Jul 21, 2017·International Journal of Retina and Vitreous·Rayan A AlshareefJay Chhablani
Mar 27, 2020·International Journal of Molecular Sciences·Saikat DewanjeeVincenzo De Feo
Jun 15, 2017·Ophthalmic Surgery, Lasers & Imaging Retina·Omer KartiBehzat Ozkan
Jan 17, 2020·Acta Ophthalmologica·Shakoor Ba-AliHenrik Lund-Andersen
Sep 6, 2019·Journal of Ophthalmology·Elena Garcia-MartinMaria Satue
Feb 27, 2021·International Ophthalmology·Dalia SabryAmr Mohammed Elsayed Abdelkader
Mar 25, 2021·Current Eye Research·Tuna Celik BuyuktepeEmin Özmert
Nov 15, 2020·Progress in Retinal and Eye Research·Deoye Tonade, Timothy S Kern
Apr 15, 2021·Klinische Monatsblätter für Augenheilkunde·Tugba CetinkayaCetin Akpolat
Apr 20, 2021·Investigative Ophthalmology & Visual Science·Andreas PollreiszUrsula Schmidt-Erfurth
May 7, 2021·International Ophthalmology·Deepak SoniBrijesh Takkar
Oct 18, 2020·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Cetin AkpolatFikriye Ordulu
Aug 6, 2021·Clinical Ophthalmology·Patricia UdaondoJosé María Ruiz-Moreno

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Software Mentioned

SPSS
FoveaFinder
Carl Zeiss OCT
FastTrac

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