Diabetic Myonecrosis: A Diagnostic and Treatment Challenge in Longstanding Diabetes

Case Reports in Endocrinology
Lima LawrenceVinni Makin

Abstract

Diabetes mellitus is associated with microvascular and macrovascular complications; the most commonly recognized ones include diabetic nephropathy, retinopathy, and neuropathy. Less well-known complications are equally important, as timely recognition and treatment are essential to decrease short- and long-term morbidity. Herein, we describe a case of a 41-year-old female with longstanding, uncontrolled type 2 diabetes, who presented with classical findings of diabetic myonecrosis. Our patient underwent extensive laboratory and imaging studies prior to diagnosis due to its rarity and similarity in presentation with other commonly noted musculoskeletal conditions. We emphasize the clinical presentation, laboratory and imaging findings, treatment regimen, and prognosis associated with diabetic myonecrosis. Diabetic myonecrosis is a rare complication of longstanding, poorly controlled diabetes mellitus. The diagnosis requires a high index of suspicion in the right clinical setting: acute onset nontraumatic muscular pain with associated findings on clinical exam, laboratory studies, and imaging. While the short-term prognosis is good, the recurrence rate remains high and long-term prognosis is poor given underlying uncontrolled dia...Continue Reading

References

Jul 15, 2004·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·T Jared BunchPatrick W Eiken
Jul 21, 2015·Diabetes Research and Clinical Practice·T JoshiJ Luu
Mar 13, 2018·World Journal of Nephrology·Tuck Yean Yong, Kareeann Sok Fun Khow

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Citations

Jun 16, 2021·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Saikrishna PatibandlaSima S Pendharkar
Jul 21, 2021·BMJ Case Reports·Jordan SimEugene Low

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Methods Mentioned

BETA
X-ray
ESR
biopsy

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