Diabetic myonecrosis: an uncommon diabetic complication

Endocrinology, Diabetes & Metabolism Case Reports
Punith KempegowdaQuratul-Ain Altaf

Abstract

Diabetic myonecrosis, also known as diabetic muscle infarction is a rare complication of diabetes mellitus usually associated with longstanding suboptimal glycaemic control. Although theories of atherosclerosis, diabetic microangiopathy, vasculitis, ischaemia-reperfusion injury and hypercoagulable state have been proposed to explain the pathophysiology, none of these have been able to individually explain the pathophysiology in entirety. Diabetic renal disease is the most common risk factor for developing DMN and its recurrence. The diagnosis is often missed due to lack of awareness and the presentation mimicking other conditions associated with DM. The routine laboratory investigations are often non-specific and do not provide much value in the diagnosis as well. Muscle biopsy can provide a definite diagnosis but is not currently recommended due to its invasiveness and association with prolonged time to symptoms resolution. Magnetic resonance imaging, in combination with classic history and risk factors can clinch the diagnosis. Treatment is generally analgesia and rest, although the former's use may be limited in the presence of renal disease. Diabetic myonecrosis is a rare complication of diabetes mellitus associated with lo...Continue Reading

Citations

Nov 11, 2020·Emergency Radiology·Paul L WassermanDheeraj Reddy Gopireddy

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Methods Mentioned

BETA
X-ray
biopsy
ESR

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