Diabetic osteopathy

Medicinski pregled
Jana Ilić, Branka Kovacev

Abstract

The aim of this study was to point out some dilemmas about the existence and pathogenesis of primary diabetic osteopathy as a separate entity, based on currently available studies. Expert disagreements are present not only about the occurrence of generalized osteopathy with diabetic disease, but also about direct relationship between metabolic diabetes control and bone metabolism and influence of disease duration and sex on bone changes. Decreased bone formation is the basic mechanism leading to decreased bone mass. Biochemical markers showed no clear connection with bone density measurement. Insulin and insulin-like growth facotr (IGF) affect bone metabolism. OSTEOPATHY IN PATIENTS WITH DIABETIC DISEASE-TYPE1: Some clinical studies have shown that patients with diabetic disease-type have a mild decrease in bone mass, while others have not presented such results. OSTEOPATHY IN PATIENTS WITH DIABETIC DISEASE-TYPE2: In patients with diabetic disease-type 2 the risk for osteopathy is even less defined. Patients treated with oral hypoglycemics present with higher decrease of bone mass has than patients treated with insulin therapy. This could partly be explained by anabolic effects of insulin on bones. Literature data are contradic...Continue Reading

References

Sep 1, 1991·Metabolism: Clinical and Experimental·T F RoeV Gilsanz
Jan 1, 1990·Bone and Mineral·G WeberG Chiumello
Apr 1, 1989·Diabetes Research and Clinical Practice·M LeonF Hawkins
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Jul 20, 2001·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·G Leidig-Bruckner, R Ziegler

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Citations

Sep 26, 2008·Vojnosanitetski pregled. Military-medical and pharmaceutical review·Miljanka VuksanovićBranka Zerajić

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