Diabetic retinopathy and risk of heart failure

Journal of the American College of Cardiology
Ning CheungARIC (Atherosclerosis Risk In Communities) Study Investigators

Abstract

The purpose of this study was to examine the association of diabetic retinopathy with incident heart failure (HF). Microvascular disease might play a more prominent role in the pathogenesis of diabetic cardiomyopathy, a major cause of HF in diabetes. Whether diabetic retinopathy, a microvascular complication of diabetes, predicts HF is unclear. A population-based study included 1,021 middle-aged type 2 diabetic persons with normal renal function and free of clinical coronary heart disease or HF at baseline. Diabetic retinopathy signs were graded from retinal photographs. Incident HF events were prospectively identified from hospital stay and death records. There were 125 (12.8%) participants with diabetic retinopathy. After 9-year follow-up, 106 (10.1%) participants developed incident HF events. Persons with retinopathy were more likely to develop HF (cumulative incidence of 21.6%) than those without retinopathy (cumulative incidence of 8.5%). After controlling for age, gender, race, smoking, diabetes duration, insulin use, blood pressure, lipid profile, and other risk factors, participants with retinopathy had more than 2.5-fold higher risk of developing HF than those without retinopathy (hazard ratio [HR] 2.71; 95% confidence...Continue Reading

References

May 1, 1988·The American Journal of Cardiology·K TakenakaT Sugimoto
Jul 1, 1974·The American Journal of Cardiology·W B KannelW P Castelli
Feb 14, 1980·The New England Journal of Medicine·S M FactorT Minase
Dec 1, 1996·Diabetes Care·H MiettinenM Laakso
Oct 8, 1997·Journal of the American College of Cardiology·T AkasakaJ Yoshikawa
Nov 24, 1999·Archives of Ophthalmology·R KleinK J Cruickshanks
Mar 7, 2002·JAMA : the Journal of the American Medical Association·Tien Yin WongLarry D Hubbard
Jul 27, 2002·Journal of the American College of Cardiology·Takayuki OnoSoichiro Kitamura
Apr 23, 2003·Journal of the American College of Cardiology·Marcelo F Di CarliJoel Ager
Sep 30, 2003·Diabetes Care·Alain G BertoniFrederick L Brancati
Feb 28, 2004·Diabetes Care·Alain G BertoniDavid C Goff
Feb 1, 2005·Journal of the American College of Cardiology·Carlo BriguoriAntonio Colombo
Sep 20, 2006·Hormones : International Journal of Endocrinology and Metabolism·George IoannidisNicolaos Thalassinos
Oct 21, 2006·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Takayuki OhnoShinichi Takamoto
Dec 30, 2006·Stroke; a Journal of Cerebral Circulation·Ning CheungTien Y Wong
Mar 9, 2007·Journal of the American Society of Nephrology : JASN·Anna KottgenJosef Coresh
Jun 27, 2007·Circulation·Sihem Boudina, E Dale Abel
Sep 13, 2007·JAMA : the Journal of the American Medical Association·A Michael LincoffSteven E Nissen
Sep 13, 2007·JAMA : the Journal of the American Medical Association·Sonal SinghCurt D Furberg
Nov 13, 2007·Journal of Cardiac Failure·Ning Cheung, Tien Yin Wong

❮ Previous
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Citations

Nov 26, 2008·Current Treatment Options in Cardiovascular Medicine·David Aguilar
Feb 2, 2013·Diabetes Research and Clinical Practice·Soichi KuriokaKeisuke Yoshimoto
Nov 24, 2012·Ophthalmology·Ryo KawasakiUNKNOWN Japan Diabetes Complications Study Group
Jun 28, 2011·Journal of Cardiac Failure·Yasuharu TakedaKazuhiro Yamamoto
Jun 29, 2010·Lancet·Ning CheungTien Yin Wong
Feb 4, 2010·Ophthalmology·Ecosse L LamoureuxTien Y Wong
Mar 3, 2009·American Heart Journal·David AguilarCraig L Hanis
Feb 6, 2008·Progress in Retinal and Eye Research·Ning Cheung, Tien Y Wong
Jun 3, 2008·Diabetic Medicine : a Journal of the British Diabetic Association·V S E JeganathanY Wong
Feb 11, 2014·Journal of cardiology·Akihito TanakaToyoaki Murohara
Mar 22, 2014·Biochemical Society Transactions·Branka VulesevicErik J Suuronen
Apr 14, 2016·Scandinavian Journal of Clinical and Laboratory Investigation·Anne Pernille Ofstad
Jun 9, 2015·Journal of Diabetes and Its Complications·Stefano BonapaceGiovanni Targher
Apr 19, 2008·Journal of the American College of Cardiology·Hector O Ventura, Madhavi Reddy
Nov 11, 2008·Journal of the American College of Cardiology·W H Wilson Tang, Gary S Francis
Feb 18, 2015·Diabetes Research and Clinical Practice·Ying WangThomas H Marwick
Aug 16, 2014·Journal of Diabetes and Its Complications·Amy K MottlJohn Buse
Jul 19, 2011·Atherosclerosis·R S RosensonP M Dodson
Aug 2, 2014·Clinical Therapeutics·Jen-Chieh LinMei-Shu Lai
May 6, 2011·Diabetes Care·Markku Laakso
May 18, 2016·International Journal of Cardiology·Tyler Hyungtaek RimSung Soo Kim
May 30, 2014·Journal of Traditional and Complementary Medicine·Yen-Chang LinPung-Ling Huang
Apr 19, 2016·PloS One·Bárbara OliveirosMiguel Castelo-Branco
Jun 10, 2011·Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease·Christopher J LockhartGary E McVeigh
Apr 15, 2009·Clinical Science·Omar AsgharRayaz A Malik
Feb 7, 2014·Circulation Journal : Official Journal of the Japanese Circulation Society·Yasuko K Bando, Toyoaki Murohara

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