PMID: 9640190Jun 26, 1998Paper

Diabetic retinopathy in Down's syndrome

The British Journal of Ophthalmology
T FulcherN O'Meara

Abstract

To determine the prevalence of diabetic retinopathy in patients with Down's syndrome and diabetes mellitus. Nine patients with Down's syndrome and diabetes mellitus were assessed. Factors recorded included type and duration of diabetes, level of diabetic control, blood pressure, urinalysis, and results of ophthalmological examination. The duration of diabetes ranged from 8 to 41 years (mean 17.6 years). All had satisfactory glycaemic control and blood pressure measurements on the low side of normal (mean 106.6/70 mm Hg). One patient had early background diabetic retinopathy. The remainder had no evidence of diabetic retinopathy. The low prevalence of diabetic retinopathy in these Down's syndrome patients, despite the long duration, is an interesting finding. It suggests some inherent protective factor against the development of diabetic retinopathy in this patient subgroup.

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Citations

Jan 18, 2006·Annual Review of Medicine·Judah Folkman
May 7, 2010·Journal of Oncology·Fernando Nussenbaum, Ira M Herman
Sep 15, 2010·BMC Medical Genomics·Valerio CostaClaudio Napoli
Nov 26, 2010·Pediatrics·Nansi S BoghossianUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
Jun 21, 2017·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Ningqiang MaHelong Zhang
Nov 26, 2004·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Judah Folkman
Aug 25, 2010·European Journal of Clinical Investigation·Eleonora SalvoliniRoberto Di Primio
Jul 17, 2015·Journal of Korean Neurosurgical Society·Ji Hoon PhiSeung-Ki Kim
Oct 2, 2009·The Journal of Craniofacial Surgery·Sandra Ryeom, Judah Folkman
Mar 24, 2020·Ophthalmic Genetics·Lavinia PostolacheGeorges Casimir
Apr 28, 2020·American Journal of Medical Genetics. Part a·George CaponeUNKNOWN Down Syndrome Medical Interest Group (DSMIG-USA) Adult Health Workgroup
Nov 2, 2020·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Hikaru NakamuraYoshiharu Tokunaga
Jul 22, 2015·Pediatrics·Tammy Z MovsasIra H Gewolb

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