Abstract
A novel diagnostic method using the standard deviation (SD) value of apparent diffusion coefficient (ADC) by diffusion-weighted (DWI) magnetic resonance imaging (MRI) is applied for differential diagnosis of primary chest cancers, metastatic tumors and benign tumors. This retrospective study enrolled 27 patients (20 males, 7 female; age, 15-85; mean age, 68) who had thoracic mass lesions in the last three years and underwent an MRI chest examination at our institution. In total, 29 mass lesions were analyzed using SD of ADC and DWI. Lesions were divided into five groups: Primary lung cancers (N = 10); esophageal cancers (N = 5); metastatic tumors (N = 8); benign tumors (N = 3); and inflammatory lesions (N = 3). Quantitative assessment of MRI parameters of mass lesions was performed. The ADC value was acquired based on the average of the entire tumor area. The error-plot, t-test and the area under receiver operating characteristic (AUC) were applied for statistical analysis. The SD of ADC value (mean±SD) was (4.867±1.359)×10-4 mm2/sec in primary lung cancers, and (3.598±0.350)×10-4 mm2/sec in metastatic tumors. The SD of ADC values of primary lung cancers and metastatic tumors (P < 0.05) were significantly different and the AUC...Continue Reading
References
Aug 3, 1999·AJR. American Journal of Roentgenology·T KimH Nakamura
Jul 2, 2002·Radiology·Petra MürtzHans H Schild
Feb 22, 2003·European Journal of Radiology·Andreas M HernethMark Bednarski
Apr 3, 2007·Radiology·Munetaka MatobaTutomu Sakuma
Oct 6, 2007·Chest·Momen M WahidiUNKNOWN American College of Chest Physicians
Oct 6, 2007·European Radiology·Shinya FujiiToshihide Ogawa
Jul 24, 2008·AJR. American Journal of Roentgenology·Shiro SatohYasuyuki Endo
Sep 30, 2008·Journal of Magnetic Resonance Imaging : JMRI·Seung Soo LeeMoon-Gyu Lee
Feb 4, 2009·Neoplasia : an International Journal for Oncology Research·Anwar R PadhaniPeter L Choyke
May 8, 2009·Radiology·Tomohiro UtoKingo Chida
Feb 18, 2010·Journal of Thoracic Imaging·Hans-Ulrich Kauczor, Sebastian Ley
Dec 7, 2010·Magnetic Resonance Imaging Clinics of North America·Antonio LunaPilar Caro
Mar 1, 2011·European Journal of Radiology·Mehmet Ruhi OnurErcan Kocakoç
Mar 14, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Benedikt A PoserV Andrew Stenger
Jun 15, 2012·Insights Into Imaging·M A VermoolenR A J Nievelstein
Oct 19, 2012·Radiology and Oncology·Sevtap GümüştaşSevgiye Kaçar Ozkara
Aug 3, 2013·Journal of Magnetic Resonance Imaging : JMRI·Ho Yun LeeJoungho Han
Dec 25, 2013·European Journal of Radiology·Gregor SommerMichael Puderbach
Nov 20, 2014·Gastroenterology Report·Jiaying GongZhiyang Zhou
Apr 2, 2015·Annals of Saudi Medicine·Lama NazerMonther Qandeel