Diagnoses rendered on prostate needle biopsy in community hospitals

The Prostate
M H WeinsteinJ I Epstein

Abstract

Reported incidences of various diagnoses made on needle biopsy of the prostate vary significantly in the literature, most of which has originated from large, academic medical centers. We recorded all the prostate needle biopsy results from three community hospitals for 1990-1993 to determine the rates of, and trends in, various diagnoses in these practices. Hospital H1 (1,192 cases) halved the rate of atypical, nondefinitive diagnoses from 11.8% in 1990 to 5.7% in 1993 (P < 0.001). The rate at H2 (2,792 cases) remained essentially unchanged at 5.95+/-0.55%, and H3 (1,306 cases) went from 2.3% to 6.0% (0.1 < P < 0.2). In the setting of an atypical, nondefinitive diagnosis, H1 and H2 recommended repeat biopsy less than 7% of the time. H3 made this recommendation in an average of 22.1% of atypical cases. Annual rates of high-grade prostatic intraepithelial neoplasia (PIN) showed no trend over time, and averaged 2.0% (1.2-3.25%) at H1 and 1.2% (0.3-2.0%) at H2. The diagnosis was never made at H3. The fraction of cancers diagnosed as low-grade (Gleason sum < or = 4) showed a statistically significant decreasing trend over time at all three hospitals (P < 0.05). These data are compared with those from the Johns Hopkins Hospital (JHH)...Continue Reading

References

Aug 1, 1991·Urology·J N Kabalin, R Kessler
Apr 27, 1989·The New England Journal of Medicine·S Greenfield
Apr 1, 1982·Scientific American·J Wennberg, A Gittelsohn
Sep 1, 1995·British Journal of Urology·S AboseifP R Carroll
Nov 1, 1995·The Journal of Urology·D G BostwickK Frankel
Aug 1, 1995·The American Journal of Surgical Pathology·J I EpsteinT M Wheeler
Jun 1, 1993·Human Pathology·M H Weinstein, J I Epstein
Aug 1, 1994·The American Journal of Surgical Pathology·D G Bostwick

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Citations

Oct 3, 2007·Prostate Cancer and Prostatic Diseases·G Godoy, S S Taneja
Jun 14, 2000·Mayo Clinic Proceedings·G W Moore, G M Hutchins
May 8, 2001·American Journal of Clinical Pathology·P Thorson, P A Humphrey
Aug 30, 2001·Hematology/oncology Clinics of North America·M J Putzi, A M De Marzo

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