PMID: 8598962Mar 1, 1996Paper

Diagnosing gestational diabetes mellitus: use of a glucose screen without administering the glucose tolerance test

Obstetrics and Gynecology
H J LandyM J O'Sullivan

Abstract

To determine if a 1-hour glucose screen value could be identified, above which gestational diabetes mellitus could be diagnosed without the 3-hour oral glucose tolerance test (GTT). Demographic, historic, obstetric, and neonatal data from 514 singleton pregnancies with glucose screen values at least 140 mg/dL followed by a GTT were reviewed (312 patients with normal GTTs and 202 with gestational diabetes mellitus). Statistical analyses used chi2, Fisher exact, Student t, and Mann-Whitney tests. After determining the optimal glucose screen cutoff point using receiver operating characteristic curve analyses, patients were regrouped according to this value and analyzed further. The optimal cutoff point for the upper limit of the glucose screen was determined to be 186 mg/dL (95.9% specificity, 98.2% negative predictive value, 36.1% sensitivity, and 19.6% positive predictive value). Comparison of patients with elevated screens and normal GTTs versus those with gestational diabetes revealed significant differences only regarding a history of gestational diabetes mellitus and neonatal hypoglycemia in the studied pregnancy. Those with screens greater than 185 mg/dL behaved like diabetic patients and, when compared with subjects with s...Continue Reading

Citations

Jul 21, 2000·The Journal of Maternal-fetal Medicine·K DangE A Reece
Feb 26, 2000·Diabetic Medicine : a Journal of the British Diabetic Association·M E GriffinR G Firth
Oct 29, 2003·Obstetrical & Gynecological Survey·Alex C VidaeffSusan M Ramin
Sep 6, 2013·Clinical Obstetrics and Gynecology·Edmond A Ryan
Jun 28, 2008·Journal of Women's Health·Lisa Chasan-TaberGlenn Markenson
Jan 23, 2016·Journal of Perinatology : Official Journal of the California Perinatal Association·L A TemmingA G Cahill
May 16, 2014·Canadian Journal of Diabetes·David ThompsonChristina Vinokuroff
Jun 13, 2015·Diabetologia·Raziel Rojas-RodriguezTiffany A Moore Simas
Apr 28, 2006·American Journal of Obstetrics and Gynecology·Robert P KauffmanJames W Van Hook
Nov 28, 2006·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Yvonne W ChengAaron B Caughey
May 2, 2006·American Journal of Obstetrics and Gynecology·Sarah FriedmanOvadia Abulafia
May 21, 2016·Obstetrics & Gynecology Science·Hyun-Hwa ChaJong-Hwa Kim
Nov 4, 2008·Obstetrics and Gynecology·Teresa A HillierDavid J Pettitt
Mar 20, 2020·Archives of Gynecology and Obstetrics·Sivan Zuarez-EastonRaed Salim

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