Diagnosis and management of hypertension in obesity

Obesity Reviews : an Official Journal of the International Association for the Study of Obesity
K Narkiewicz

Abstract

Cardiovascular risk in a patient with obesity hypertension increases with the extent of risk factor clustering. It is therefore important to determine the global risk of a patient with hypertension rather than to focus solely on blood pressure. Every hypertensive should be screened for other than blood pressure risk factors, target organ damage and concomitant diseases or accompanying clinical conditions. Assessment of blood pressure and target organ damage might be more difficult in obese hypertensives than in normal-weight patients. Intensive lifestyle interventions can reduce weight, and decrease blood pressure and cardiovascular risk in obese hypertensive patients. Current guidelines do not provide specific recommendation for pharmacological management of the hypertensive patients with obesity. Recent trials have consistently shown that therapy involving beta-blockers and diuretics may induce more new-onset diabetes compared with other combination therapies. Several lines of evidence suggest that anti-hypertensive agents that block the renin-angiotensin system may be especially beneficial in treating obese hypertensive patients. Hypertension management in obese individuals is complicated by poorer response to treatment, and...Continue Reading

References

Jan 1, 1992·Hypertension·A P Rocchini
Jan 1, 1991·Circulation·K M AndersonW B Kannel
Jun 1, 1994·Circulation·U ScherrerP Nicod
Nov 1, 1993·Circulation·D PerloffB Z Morgenstern
Jan 24, 1998·Annals of Internal Medicine·Z HuangG A Colditz
Feb 7, 1998·Hypertension·E W ShekJ E Hall
Nov 18, 1998·Journal of Human Hypertension·B KuchH W Hense
Aug 17, 1999·Journal of Human Hypertension·I S OkosunR S Cooper
Mar 18, 2000·Hypertension·S JuliusP Palatini
Jun 17, 2000·Hypertension·J P GreenwoodD A Mary
Jan 4, 2001·The New England Journal of Medicine·F M SacksUNKNOWN DASH-Sodium Collaborative Research Group
Feb 28, 2001·Obesity Research·C D BrownM Horan
Mar 29, 2001·Current Hypertension Reports·A M SharmaT Pischon
May 2, 2001·Journal of Hypertension·A M SharmaJ Scholze
Nov 29, 2001·Journal of Hypertension·A G LoganT D Bradley
Feb 28, 2002·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Arya M Sharma, Stefan Engeli
Mar 28, 2002·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·A M Sharma
Apr 3, 2002·Annals of Internal Medicine·Seamus P WheltonJiang He
May 7, 2002·American Journal of Hypertension·James OuzanMichel Mertes
Jun 6, 2002·Cardiology in Review·Edward D Frohlich
Nov 29, 2002·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·A M Sharma
Mar 8, 2003·Hypertension·John E Hall
Jun 5, 2003·Journal of Hypertension·UNKNOWN European Society of Hypertension-European Society of Cardiology Guidelines Committee
Jun 6, 2003·European Heart Journal·R M ConroyUNKNOWN SCORE project group
Jan 21, 2004·Hypertension·Theodore L Goodfriend, David A Calhoun
Mar 24, 2004·Hypertension·Paolo VerdecchiaCarlo Porcellati
Apr 8, 2004·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Kevin P Davy, John E Hall
Oct 16, 2004·American Journal of Hypertension·Peter BramlageArya M Sharma
Dec 8, 2004·Current Pharmaceutical Design·Marion R Wofford, John E Hall
Jan 5, 2005·Hypertension·Stefan EngeliArya M Sharma
Feb 3, 2005·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J JordanA M Sharma
Feb 18, 2005·Journal of Hypertension·Karin A M Jandeleit-DahmMark E Cooper

❮ Previous
Next ❯

Citations

Aug 5, 2008·Wiener medizinische Wochenschrift·Jörg Slany
Jul 12, 2013·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Hong Seog SeoChang Gyu Park
Mar 7, 2012·International Journal of Obesity : Journal of the International Association for the Study of Obesity·P PalatiniE Casiglia
Jul 22, 2010·Annual Review of Nutrition·Vincenzo SavicaJoel D Kopple
Oct 6, 2015·The Journal of Clinical Hypertension·Paolo PalatiniPaolo Verdecchia
Aug 23, 2011·The Medical Clinics of North America·L Romayne KurukulasuriyaJames R Sowers
Sep 9, 2008·Endocrinology and Metabolism Clinics of North America·L Romayne KurukulasuriyaJames R Sowers
Aug 13, 2011·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·J A N DorresteijnW Spiering
Jun 18, 2014·The Journal of Clinical Hypertension·Junxia ZhangBing Chen
May 8, 2018·Current Hypertension Reports·Claudia Agabiti-RoseiDamiano Rizzoni

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.