Diagnosis and management of Neuro-Behçet's disease: international consensus recommendations

Journal of Neurology
Seema KalraA H Al-Araji

Abstract

Neuro-Behçet's disease (NBD) is one of the more serious manifestations of Behçet's disease (BD), which is a relapsing inflammatory multisystem disease with an interesting epidemiology. Though NBD is relatively uncommon, being potentially treatable, neurologists need to consider it in the differential diagnosis of inflammatory, infective, or demyelinating CNS disorders. Evidence-based information on key issues of NBD diagnosis and management is scarce, and planning for such studies is challenging. We therefore initiated this project to develop expert consensus recommendations that might be helpful to neurologists and other clinicians, created through an extensive literature review and wide consultations with an international advisory panel, followed by a Delphi exercise. We agreed on consensus criteria for the diagnosis of NBD with two levels of certainty in addition to recommendations on when to consider NBD in a neurological patient, and on the use of various paraclinical tests. The management recommendations included treatment of the parenchymal NBD and cerebral venous thrombosis, the use of disease modifying therapies, prognostic factors, outcome measures, and headache in BD. Future studies are needed to validate the propose...Continue Reading

References

Mar 1, 1991·Neurology·M Z Al KawiM Banna
Dec 1, 1988·Stroke; a Journal of Cerebral Circulation·R Bonita, R Beaglehole
Jan 1, 1984·The American Journal of Medicine·J D O'DuffyN P Goldstein
Feb 1, 1984·Annals of the Rheumatic Diseases·H YaziciA Müftüoglu
Mar 1, 1980·Journal of Neurology, Neurosurgery, and Psychiatry·S MotomuraY Kuroiwa
Jul 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·B WechslerP Godeau
Jan 13, 1996·BMJ : British Medical Journal·D L SackettW S Richardson
Mar 1, 1996·Journal of Dermatological Science·Y YamakawaH Nakajima
Jan 1, 1997·Clinical Immunology and Immunopathology·S HirohataT Hashimoto
Sep 19, 1998·Journal of the Neurological Sciences·S HirohataT Hashimoto
Apr 21, 1999·QJM : Monthly Journal of the Association of Physicians·J P ZajicekD Mitchell
Nov 5, 1999·Brain : a Journal of Neurology·D KiddP Rudge
Nov 24, 1999·Journal of the Neurological Sciences·S A Al-Fahad, A H Al-Araji
Jun 27, 2001·Rheumatology·A GülG Saruhan-Direskeneli
Jun 29, 2001·Clinical Radiology·S H LeeD I Kim
Jul 14, 2001·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·J C NicholsE S Mann
Sep 7, 2002·Stroke; a Journal of Cerebral Circulation·J T Lindsay WilsonIan Bone
Feb 13, 2003·Journal of Advanced Nursing·Catherine Powell
Apr 18, 2003·Journal of Neurology, Neurosurgery, and Psychiatry·A Al-ArajiZ Al-Rawi
Aug 16, 2003·Advances in Experimental Medicine and Biology·Hirotoshi KikuchiShunsei Hirohata
Oct 15, 2003·Neuroradiology·G Akman-DemirP Serdaroglu
Dec 4, 2003·Journal of Neuroimmunology·Güher Saruhan-DireskeneliPiraye Serdaroğlu
Feb 19, 2005·Stroke; a Journal of Cerebral Circulation·J T Lindsay WilsonKeith W Muir
Mar 1, 2005·The Neurologist·Afshin Borhani HaghighiAli-Reza Nikseresht
Apr 2, 2005·The Tohoku Journal of Experimental Medicine·Handan Isin OzisikCemal Ozcan
Jun 30, 2005·Headache·Sabahattin SaipHasan Yazici
Aug 6, 2005·The Tohoku Journal of Experimental Medicine·Hulusi Kececi
Dec 6, 2005·Rheumatology International·Simone AppenzellerSandra Regina M Fernandes
Jan 24, 2006·Cephalalgia : an International Journal of Headache·E AykutluM Ertas
Feb 18, 2006·The International Journal of Neuroscience·Omer AnlarSerap G Bilgili
Jan 24, 2007·Lancet Neurology·Marie-Germaine Bousser, José M Ferro
Jan 26, 2007·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·F G Joseph, N J Scolding
Mar 6, 2007·Nature Clinical Practice. Rheumatology·Hasan YaziciSebahattin Yurdakul
Jun 28, 2007·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·N YesilotG Akman-Demir

❮ Previous
Next ❯

Citations

Mar 24, 2016·Current Treatment Options in Neurology·Murat KürtüncüGulsen Akman-Demir
May 10, 2015·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Didar UcarYilmaz Ozyazgan
Aug 17, 2016·Case Reports in Neurological Medicine·Wai Wai MillerDerrick Robertson
May 16, 2017·Expert Opinion on Biological Therapy·A C DesboisD Saadoun
Jun 2, 2017·Continuum : Lifelong Learning in Neurology·Elliot L Dimberg
Jan 15, 2017·Autoimmunity Reviews·Lívia Almeida DutraSimone Appenzeller
Jan 18, 2016·Neurología : publicación oficial de la Sociedad Española de Neurología·N FalgàsA Cervera
Feb 13, 2018·Current Opinion in Rheumatology·Fatma Alibaz-OnerHaner Direskeneli
Dec 19, 2014·The Cochrane Database of Systematic Reviews·Francesca NavaIrene Tramacere
Jun 3, 2015·International Journal of Rheumatic Diseases·Antonio VitaleLuca Cantarini
Nov 20, 2016·Arthritis Care & Research·Geoffroy VolleAlfred Mahr
Jan 12, 2017·The Korean Journal of Internal Medicine·Hee Jung RyuHan Joo Baek
Sep 29, 2015·Experimental Neurobiology·Byung-Nam YoonSeong Hye Choi
Feb 13, 2019·Current Neurology and Neuroscience Reports·Asya I WallachIlya Kister
Dec 7, 2018·Neurology India·Paola Caruso, Rita Moretti
Mar 13, 2019·International Journal of Rheumatic Diseases·Deniz AlisOsman Kizilkilic
Nov 5, 2019·Annals of Clinical and Translational Neurology·Hidehiro IshikawaHidekazu Tomimoto
Dec 25, 2019·Journal of Human Genetics·Chrysoula DimopoulouRasmus L Marvig
Apr 30, 2020·Rheumatology·Alessandra BettiolGiacomo Emmi
Feb 20, 2018·Dermatopathology·Lauren N KoDaniela Kroshinsky
Sep 21, 2019·Annals of the Royal College of Surgeons of England·A E MousaS Surash
Aug 20, 2020·Ocular Immunology and Inflammation·Shaivi A PatelMeghan K Berkenstock
Sep 9, 2019·Neuropsychology Review·Caroline A Fisher, Coco Bernard
Nov 24, 2016·Acta neurologica Belgica·Dimitri RenardEric Thouvenot
Apr 8, 2018·Clinical Medicine : Journal of the Royal College of Physicians of London·Marine Boudot de la MotteKarim Sacre
May 24, 2018·Current Neurology and Neuroscience Reports·Uğur Uygunoğlu, Aksel Siva
Jul 17, 2020·Current Pain and Headache Reports·Marianna Vinokur, John Glenn Burkett
Jul 4, 2017·Therapeutic Advances in Neurological Disorders·Sung-Min KimKazuo Fujihara
May 17, 2018·Journal of Neuroinflammation·Amna Rana, Alberto E Musto
Oct 31, 2017·International Journal of Rheumatology·Fahd AdeebAlexander D Fraser
Dec 21, 2018·BMJ Case Reports·Julia ManassonJohannes Nowatzky
Apr 3, 2019·Immunological Medicine·Fumitaka ShimizuTakashi Kanda
Nov 9, 2018·Current Opinion in Rheumatology·Uğur Uygunoğlu, Aksel Siva
Mar 16, 2019·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·P S OvcharovE L Nasonov
Oct 9, 2019·Journal of Clinical Neurology·Seung Woo KimDongsik Bang
Jan 11, 2020·Frontiers in Immunology·Alessandra BettiolGiacomo Emmi
Feb 29, 2020·BMJ Case Reports·George PanosAndreas Emmanuil
Sep 10, 2020·Clinical, Cosmetic and Investigational Dermatology·Preeyachat LimtongPintip Ngamjanyaporn
Feb 6, 2017·Clinical Medicine : Journal of the Royal College of Physicians of London·Jagdish R Nair, Robert J Moots
Jan 1, 2016·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·P S OvcharovE L Nasonov
May 30, 2017·Current Pain and Headache Reports·Jon Rosenberg, Benjamin T Galen
May 21, 2019·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Luisa BritesMariana Santiago
Aug 4, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Müge Kuzu KumcuCanan Yücesan
Aug 25, 2020·Current Treatment Options in Neurology·David A Lapides, Mark M McDonald

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
ESR
genotyping

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of General Internal Medicine
Eric Michael Fountain, Anjali Dhurandhar
Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Ali AlrefaiHassan Al-Balas
© 2021 Meta ULC. All rights reserved