Optic nerve gliomas are highly variable tumours with an unpredictable clinical course. Consequently, the diagnosis and management of these tumours remains complex and a standardised management strategy does not exist. In this paper we describe a patient with optic nerve glioma treated at our institution and then review recent advances made in the diagnosis and treatment of these tumours over the past 10 years. Our aim is to clarify current best practice in the management of optic nerve gliomas.
Emergence of optic pathway gliomas in children with neurofibromatosis type 1 after normal neuroimaging results
Definitive radiation therapy in the management of symptomatic patients with optic glioma. Survival and long-term effects
Visual morbidity with chiasmal glioma. Long-term studies of visual fields in untreated and irradiated cases
Natural history of optic pathway tumors in children with neurofibromatosis type 1: a longitudinal study
Optic pathway gliomas in children with neurofibromatosis 1: consensus statement from the NF1 Optic Pathway Glioma Task Force
Carboplatin and vincristine chemotherapy for children with newly diagnosed progressive low-grade gliomas
Childhood optic chiasm gliomas: radiographic response following radiotherapy and long-term clinical outcome
When do children with optic pathway tumours need treatment? An oncological perspective in 106 patients treated in a single centre
MRI and clinical differences between optic pathway tumours in children with and without neurofibromatosis
Visual loss in children with neurofibromatosis type 1 and optic pathway gliomas: relation to tumor location by magnetic resonance imaging
Low grade chiasmatic-hypothalamic glioma-carboplatin and vincristin chemotherapy effectively defers radiotherapy within a comprehensive treatment strategy -- report from the multicenter treatment study for children and adolescents with a low grade glioma -- HIT-LGG 1996 -- of the Society of Pediatric Oncology and Hematology (GPOH)
Bilateral optic pathway glioma with intracranial calcification: magnetic resonance imaging and magnetic resonance spectroscopy findings
Fractionated stereotactic radiotherapy using Novalis for confined intra-orbital optic nerve glioma in pediatric patient
The rare event of optic-chiasmatic hemorrhagic low grade glioma in adulthood. Considerations on treatment strategy
Role of visual evoked potentials in the assessment and management of optic pathway gliomas in children
Surgical Management of Pilocytic Astrocytoma of the Optic Nerve: A Case Report and Review of the Literature
Visual outcomes after chemotherapy for optic pathway glioma in children with and without neurofibromatosis type 1: results of the International Society of Paediatric Oncology (SIOP) Low-Grade Glioma 2004 trial UK cohort
Long-term clinical and visual outcomes after surgical resection of pediatric pilocytic/pilomyxoid optic pathway gliomas.
The role of diffusion tensor tractography in the surgical treatment of pediatric optic chiasmatic gliomas
The Visual Acuity Outcome and Relevant Factors Affecting Visual Improvement in Pediatric Sporadic Chiasmatic-Hypothalamic Glioma Patients Who Received Surgery
Demographic and prognostic factors of optic nerve astrocytoma: a retrospective study of surveillance, epidemiology, and end results (SEER).
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