Diagnosis and management of pediatric brain-stem gliomas

Journal of Neurosurgery
A R StroinkR P Humphreys

Abstract

The authors reviewed the cases of 49 children, ranging in age from 9 months to 15 years, who were diagnosed by computerized tomography (CT) as having brain-stem glioma. Four distinct groups of brain-stem gliomas were identified based on CT scan characteristics: Group I included isodense contrast-enhancing tumors that were dorsally exophytic into the fourth ventricle; Group II(a) included hypodense nonenhancing intrinsic tumors of the brain stem; Group II(b) included intrinsic tumors of the brain stem with hyperdense exophytic components extending ventrally and laterally into the cerebellopontine and prepontine cisterns; Group III included intrinsic cystic tumors with contrast-enhancing capsules; and Group IV included focally intrinsic tumors of the brain stem that were isodense and enhanced brightly on administration of contrast medium. The clinical presentation, efficacy of surgical intervention, pathology, and prognosis of these tumors were correlated within these groupings. Eleven patients had Group I tumors, all of which were surgically resected; 10 of the 11 lesions were proven to be low-grade gliomas. These patients had an excellent prognosis; 10 of the 11 survived, with a mean follow-up period of 4.5 years. There were 18...Continue Reading

References

Dec 1, 1977·Cancer·J R FarwellJ T Flannery
Apr 1, 1977·Seminars in Roentgenology·M GadoM Mikhael
Jan 1, 1979·Child's Brain·D H ReigelJ E Woodford
Jun 1, 1971·Journal of Neurosurgery·K R LassiterD L Kelly
Oct 1, 1972·Journal of Neurology, Neurosurgery, and Psychiatry·G S GoldenJ H French
Sep 1, 1974·Radiology·N AbramsonP J Cavanaugh
Jun 1, 1981·Journal of Neurosurgery·D S FultonC B Wilson
Jul 1, 1982·The British Journal of Surgery·C SmadjaL H Blumgart
Jan 1, 1982·International Journal of Cardiology·A H Harken
Jan 1, 1980·Radiology·L T BilaniukL Schut
Jun 1, 1980·Cancer·P LittmanL Schut

❮ Previous
Next ❯

Citations

Jan 1, 1987·Journal of Neuro-oncology·H S Friedman, W J Oakes
Nov 1, 1988·Journal of Neuro-oncology·S NishioJ Tateishi
Jan 1, 1989·Neuroradiology·J V ByrneI F Moseley
Aug 1, 1993·Journal of Neuro-oncology·M E HebertO B Boyko
Feb 1, 1993·Journal of Neuro-oncology·M C Chamberlain
Jul 19, 2006·Pediatric Radiology·Jong Won KwonKyung Mo Yeon
Nov 6, 2007·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Raj Kumar, Samir K Kalra
May 3, 2011·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Soumen KhatuaJohn R W Kestle
Oct 12, 2012·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Ji Hoon PhiSeung-Ki Kim
Jul 1, 1990·Seminars in Roentgenology·R R Smith
Sep 1, 1996·International Journal of Pediatric Otorhinolaryngology·K ItoT Semba
Dec 4, 2003·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Kazuhiko KyoshimaJun Nakayama
Jul 16, 2013·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Ranjith BabuCory Adamson
Feb 11, 1998·International Journal of Radiation Oncology, Biology, Physics·C R Freeman, J P Farmer
Aug 1, 1988·International Journal of Radiation Oncology, Biology, Physics·C R FreemanD Norris
Sep 10, 1998·Journal of the National Cancer Institute·M A SmithR Simon
Jun 24, 1999·Journal of the National Cancer Institute·M S LinetS S Devesa
May 20, 1999·Archives of Disease in Childhood·D A WalkerM Sokal
Jun 3, 2011·Journal of Neurosurgery. Pediatrics·S Jared BroadwayFrederick A Boop
Jan 8, 2013·Journal of Neurosurgery. Pediatrics·Paul KlimoRobert A Sanford
Aug 1, 1987·Journal of Neurosurgery·F J Epstein
May 1, 1989·Journal of Neurosurgery·M S EdwardsP Silver
Jun 1, 1991·Journal of Neurosurgery·P L MayD C Harwood-Nash
Mar 1, 1993·Journal of Neurosurgery·F J Epstein, J P Farmer
Dec 31, 1997·Journal of Neurosurgery·C StraussR Fahlbusch
Nov 30, 1999·Journal of Neurosurgery·C StraussR Fahlbusch
Jun 17, 2006·Journal of Neurosurgery·Jessica TernierChristian Sainte-Rose
May 2, 2008·Journal of Neurosurgery. Pediatrics·R Michael Scott
Jul 31, 1999·Pediatric Neurology·N L AntunesM Souweidane
Feb 1, 1992·Italian Journal of Neurological Sciences·G Lo RussoA L Benabid
Jan 1, 1994·Acta neurochirurgica·C LaprasJ Guyotat
Jan 1, 1992·Acta neurochirurgica·G P KratimenosD G Thomas
Jun 1, 1995·Medical and Pediatric Oncology·P MolloyS Rebsamen
Jul 1, 1989·International Journal of Radiation Oncology, Biology, Physics·Y ShibamotoM Abe
Jan 15, 1993·International Journal of Radiation Oncology, Biology, Physics·M J GuineyK Narayan
May 28, 2011·Pediatric Blood & Cancer·Iris FriedUri Tabori
Oct 1, 1988·Surgical Neurology·R A SanfordM E Cohen
Nov 12, 2015·Journal of Pediatric Neurosciences·Sandi LamStephanie Melkonian

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
biopsies
surgical resection

Related Concepts

Related Feeds

Brain Stem Neoplasms

Brain Stem Neoplasms are cancers that are common in children and can occur in the mesencephalon, pons or medulla oblongata. Discover the latest research on Brain Stem Neoplasms here.