Diagnosis and treatment of cluster headache

Seminars in Neurology
David J Capobianco, D W Dodick

Abstract

Cluster headache is an uncommon yet distinctive neurovascular syndrome occurring in either episodic or chronic patterns. The most unique feature of cluster headache is the unmistakable circadian and circannual periodicity. The attacks are stereotypical, that is, of extreme intensity, of short duration, occurring unilaterally, and associated with robust signs and symptoms of autonomic dysfunction. Unlike migraine, during an attack the patient with cluster headache often paces about. Attacks frequently occur at night, awakening the patient from sleep. Although the pathophysiology of cluster headache remains to be fully elucidated, several seminal observations have recently been made. The medical treatment of cluster headache includes acute, transitional, and maintenance prophylaxis. Agents used for acute therapy include inhalation of oxygen and triptans, such as sumatriptan, and dihydroergotamine. Transitional prophylaxis refers to the short-term use of fast-acting agents. This typically involves either corticosteroids or ergotamine derivatives. The mainstay of prophylactic therapy is verapamil. Lithium, divalproex sodium, or topiramate may also be useful. As the sophistication of functional neuroimaging increases, so too will ou...Continue Reading

Citations

Mar 21, 2007·Current Pain and Headache Reports·Susan W BronerChristine L Lay
May 1, 2007·Nature Neuroscience·Takahiro TakanoMaiken Nedergaard
Jul 21, 2011·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·A SteinbergA I M Nilsson Remahl
Aug 23, 2011·Neuromodulation : Journal of the International Neuromodulation Society·Antonios MammisAlon Y Mogilner
May 2, 2008·Expert Opinion on Investigational Drugs·Nir Barak
Jan 29, 2016·Diabetes Research and Clinical Practice·Yulia KhodnevaMonika M Safford
Aug 6, 2009·Progress in Neurobiology·Francesca GallettiPaola Sarchielli
Jul 10, 2007·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Ramesh Balasubramaniam, Gary D Klasser
Jul 22, 2014·Journal of Oral Rehabilitation·H YataniG M Heir
Dec 3, 2008·The Journal of the American Dental Association·Ramesh BalasubramaniamRobert Delcanho
Sep 28, 2016·The Journal of Headache and Pain·Michail Vikelis, Alan M Rapoport
Jul 27, 2010·Cephalalgia : an International Journal of Headache·Sanjay PrakashBhavna V Chavda
Dec 1, 2012·Cephalalgia : an International Journal of Headache·Elizabeth LerouxAnne Ducros
Dec 29, 2015·The Cochrane Database of Systematic Reviews·Michael H BennettStephanie Weibel
Oct 12, 2018·Neuromodulation : Journal of the International Neuromodulation Society·Daivik B VyasCasey H Halpern
Jun 20, 2013·Ear, Nose, & Throat Journal·Edward C WuHamid R Djalilian
Feb 7, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Anaé MontaAnne Donnet
Mar 17, 2010·Neurology·Chad A Whyte, Stewart J Tepper

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