Diagnosis and treatment of necrotising otitis externa and diabetic foot osteomyelitis - similarities and differences

The Journal of Laryngology and Otology
C PeledD Kaplan

Abstract

Necrotising otitis externa is a severe inflammatory process affecting soft tissue and bone, mostly in diabetic patients. Diabetic patients are also at risk of diabetic foot osteomyelitis, another inflammatory condition involving soft tissue and bone. This review aimed to describe the similarities and differences of these entities in an attempt to further advance the management of necrotising otitis externa. A PubMed search was conducted using the key words 'otitis externa', 'necrotising otitis externa', 'malignant otitis externa', 'osteomyelitis' and 'diabetic foot'.Results and conclusionThe similarities regarding patient population and pathophysiology between necrotising otitis externa and diabetic foot osteomyelitis raise basic questions concerning the effects of long-standing diabetes on the external ear. The concordance between local swabs and bone cultures in diabetic foot osteomyelitis is less than 50 per cent. If this holds true also to necrotising otitis externa, the role of deep tissue cultures should be strongly considered. Similar to diabetic foot osteomyelitis, magnetic resonance imaging should be considered in selected necrotising otitis externa subgroups.

References

Jan 1, 1992·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J A Garcia RodriguezT López Alburquerque
Jan 1, 1992·Archives of Otolaryngology--head & Neck Surgery·H N Barrow, M J Levenson
Aug 1, 1968·The Laryngoscope·J R Chandler
Jan 23, 1982·Lancet
Jun 9, 2000·The British Journal of Radiology·M B TomasC J Palestro
Jan 22, 2002·The Laryngoscope·D W StromanW Burt
May 25, 2002·Diabetic Medicine : a Journal of the British Diabetic Association·C A AbbottUNKNOWN North-West Diabetes Foot Care Study
Jan 15, 2004·The Lancet Infectious Diseases·Jennifer Rubin GrandisVictor L Yu
Jul 28, 2004·Lancet·Daniel P Lew, Francis A Waldvogel
Apr 6, 2005·The Journal of Laryngology and Otology·N C E OkpalaM Pringle
Apr 25, 2007·Scandinavian Journal of Infectious Diseases·Woo Kyun BaeSoo Wan Kim
Aug 2, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Uri PelegDavid Cohen
Apr 4, 2008·Diabetologia·F L Game, W J Jeffcoate
Apr 17, 2008·Journal of Diabetes and Its Complications·Serkan YenerSena Yesil
Apr 26, 2008·Otolaryngologic Clinics of North America·Matthew J Carfrae, Bradley W Kesser
Jul 10, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marie T DinhNasia Safdar
Jan 2, 2009·Diabetes Research and Clinical Practice·Lawrence A LaveryBenjamin A Lipsky
Oct 25, 2011·The Journal of Laryngology and Otology·S Hollis, K Evans
May 24, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Benjamin A Lipsky Infectious Diseases Society of America
Nov 14, 2012·The Journal of Craniofacial Surgery·Emin KaramanOzgün Enver
Apr 6, 2013·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Shaun Loh, Woei Shyang Loh
Apr 20, 2013·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Pouya MahdyounNicolas Guevara
Sep 3, 2013·The Medical Clinics of North America·Edgar J G Peters, Benjamin A Lipsky
Sep 3, 2013·The Medical Clinics of North America·Frances L Game
Aug 28, 2014·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Maayan GruberRaanan Cohen-Kerem
Sep 17, 2015·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Shawn M StevensTed A Meyer
Nov 14, 2015·Journal of Orthopaedics·Leonard Charles MaraisTheo Le Roux

❮ Previous
Next ❯

Citations

Jan 25, 2020·The Annals of Otology, Rhinology, and Laryngology·Tzong-Hann YangHerng-Ching Lin
Jan 30, 2020·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Aiken DaoAaron Schindeler
Feb 14, 2020·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Chilaf PeledDaniel M Kaplan
Jun 6, 2020·The Journal of Laryngology and Otology·A A K Abdel Razek, W Mahmoud
Mar 13, 2019·SAGE Open Medical Case Reports·Marcos Frata RihlRoseane Cardoso Marchiori
Jan 12, 2021·American Journal of Otolaryngology·José Luis Treviño GonzálezJesús Eduardo Hernández de León
Jan 29, 2021·Journal of Otology·Mehdi HasnaouiKhalifa Mighri
Apr 2, 2021·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Chilaf PeledDaniel M Kaplan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.