Diagnosis, Clinical Presentations, and Outcomes of Nocardia Endophthalmitis

American Journal of Ophthalmology
Vivek Pravin DaveTaraprasad Das

Abstract

To describe the clinical presentations, diagnosis, and management outcomes of Nocardia endophthalmitis. Retrospective, interventional, multicenter case series. The study was conducted in a multicentric institutional practice setup and included 25 eyes of 25 patients with culture-proven Nocardia endophthalmitis. Anterior chamber fluid and/or vitreous and/or intraocular lens were submitted for microbiological evaluation in all cases. Patients with non-Nocardia etiology and those that were culture negative were excluded. Case records were studied and data regarding demography, clinical presentations, interventions received, and final visual and anatomic outcomes were noted. The main outcome measures were final visual outcomes and factors determining them. The mean age of the patients was 54.7 ± 22.9 years. By the etiology of infection, 18 (75%) eyes were post-cataract surgery (operated elsewhere), 3 (12.5%) eyes were posttrauma, and 3 (12.5%) eyes were endogenous. The final follow-up was a mean of 14.25 ± 30.35 months, median 2 months. The odds of a favorable outcome were 42.5 (95% confidence interval [CI] 3.15 to 571.84, P = .0047) when the vision was more than hand motions at presentation, 9.42 (95% CI 0.92 to 95.89, P = .05) in...Continue Reading

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Citations

Jul 4, 2020·Current Opinion in Organ Transplantation·Jennifer L Saullo, Rachel A Miller
Oct 7, 2020·Ocular Immunology and Inflammation·Naresh Babu KannanKim Ramasamy
Feb 6, 2021·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Sweety TiplePrajakta Kimmatkar
Jun 2, 2021·Journal of Ophthalmic Inflammation and Infection·Marie Česká BurdováDagmar Dotřelová
Jun 3, 2021·Clinical Microbiology Reviews·Sixto M LealPeter H Gilligan

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