Diagnosis of acute renal failure in very preterm infants

Biology of the Neonate
G Choker, J B Gouyon

Abstract

This study was designed to improve the definition of acute renal failure (ARF) in very preterm infants. Twenty-eight newborn infants with gestational age < or =32 weeks were prospectively studied in the first 5 days of life and made up a control group as they did not present risk factors for vasomotor renal insufficiency. Renal insufficiency was defined as an increase in daily serum creatinine concentration above the 99th interval limit obtained in this control group, i.e., 43 micromol/l on day 1 and/or 21 micromol/l on day 2 and/or 14 micromol/l/day on day 3 and/or 22 micromol/l/day on day 4. According to this definition, 20 very preterm infants with ARF were identified. As compared with the control group, the ARF group showed more prolonged oliguric episodes, lower diuresis, insufficient weight loss (in spite of a reduction in water intake) and also more episodes with natremia <130 mEq/l (35 vs. 0%; p <0.05) and/or kalemia >6 mEq/l (40 vs. 11%; p <0.05). Therefore, assessment of daily changes in serum creatinine concentration in very preterm infants allows the diagnosis of clinically significant reduction in glomerular filtration rate.

Citations

Jan 5, 2014·PloS One·Alexandra BruelEmma Allain-Launay
Jun 4, 2011·Journal of the American Society of Nephrology : JASN·Megan R SutherlandM Jane Black
Dec 19, 2009·Vojnosanitetski pregled. Military-medical and pharmaceutical review·Aleksandra DoronjskiRadojica Savić
Dec 17, 2008·Journal of Perinatology : Official Journal of the California Perinatal Association·S IacobelliJ-B Gouyon
Jul 24, 2010·Journal of Perinatology : Official Journal of the California Perinatal Association·M W WalkerA R Spitzer
Oct 1, 2011·Journal of Perinatology : Official Journal of the California Perinatal Association·S IacobelliJ B Gouyon
Apr 17, 2012·International Journal of Pediatrics·Silvia IacobelliJean-Bernard Gouyon
May 29, 2007·The Pediatric Infectious Disease Journal·Gary L DarmstadtPatricia Coffey
May 21, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Ahmet Taner ElmasSevcan Ipek
Apr 6, 2006·Seminars in Fetal & Neonatal Medicine·Nadeem E Moghal, Nicholas D Embleton
Apr 22, 2009·The Annals of Thoracic Surgery·Vladimiro L VidaGiovanni Stellin
Feb 15, 2017·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Syeda MaqsoodMaroun J Mhanna
Mar 24, 2011·Reproductive Sciences·Lina GubhajuM Jane Black
Mar 5, 2016·Journal of the American Society of Nephrology : JASN·Fanny Oliveira ArcolinoElena Levtchenko
Aug 26, 2016·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Maria Cristina AisaGian Carlo Di Renzo
May 11, 2017·Journal of Renal Injury Prevention·Vishal PandeyRupesh Raina
Jun 13, 2020·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Silvia Iacobelli, Jean-Pierre Guignard

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