Diagnosis of bovine tuberculosis using a metal oxide-based electronic nose

Letters in Applied Microbiology
Y S ChoS Oh

Abstract

Electronic noses (e-noses) have been used for environmental monitoring, standardization of medicinal flavourings, food safety tests and diagnosis of infectious diseases based on the statistical analysis of volatile organic compounds (VOCs). Bovine tuberculosis (bTB) is officially diagnosed using the intradermal skin test (IST), which is time-consuming and labour-intensive. Therefore, a more convenient and rapid test with greater sensitivity would be advantageous as prescreening test. In this study, we used a metal oxide sensor (MOS) type e-nose to analyse VOCs in a bTB-infected (n = 11) and bTB-free (n = 10) sera, from cattle whose health status was confirmed using the IST, and pathological and bacteriological examinations. The differences in VOCs from bTB-infected and bTB-free sera detected by the e-nose were statistically analysed using principal components and discriminant factor analyses. bTB-infected and bTB-free sera could be discriminated by MOS type e-nose, and analysing time per sample was only 20 min. VOC analysis using a MOS e-nose was a rapid and automated prescreening method to diagnose bTB, and can be used to select bTB-suspect cattle for IST confirmation. Further studies are required to estimate test sensitivity ...Continue Reading

References

Jun 2, 2000·Clinical Chemistry and Laboratory Medicine : CCLM·A K Pavlou, A P Turner
Dec 20, 2003·Gut·C S J ProbertN M Ratcliffe
Apr 9, 2005·Journal of Clinical Microbiology·R FendM A Chambers
Jan 22, 2008·Chemical Reviews·Frank RöckUdo Weimar
Jun 26, 2009·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·George PretiAlan Gelperin
Mar 29, 2011·Letters in Applied Microbiology·S U SavelevA De Soyza
Nov 7, 2012·Tuberculosis·Marcel BruinsAlex van Belkum
Dec 25, 2012·Sensors·Miguel Macías MacíasJuan Carlos Peguero Chamizo
Jan 5, 2014·SpringerPlus·Soad A AbdallahBashayer Al-Awadi
Apr 29, 2014·Research in Veterinary Science·Javier BezosLucas Domínguez

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Citations

Nov 16, 2016·Journal of Pediatric Gastroenterology and Nutrition·Daniel J C BerkhoutTim G J de Meij
Jun 12, 2018·Chemical Society Reviews·Yoav Y BrozaHossam Haick
Nov 13, 2020·Critical Reviews in Analytical Chemistry·P Rodríguez-HernándezV Rodríguez-Estévez
Dec 29, 2020·Animal Health Research Reviews·Hyun-Eui Park, Han Sang Yoo
Apr 13, 2021·Advanced Biology·Aylen Lisset Jaimes-MogollónRadu Ionescu
Jun 11, 2021·Frontiers in Veterinary Science·Pablo Rodríguez-HernándezJaime Gómez-Laguna

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