PMID: 9650436Jul 3, 1998Paper

Diagnosis of cerebral toxoplasmosis by a nested polymerase chain reaction: a case report

Zhonghua yi xue za zhi = Chinese medical journal; Free China ed
J J Lin, H J Harn

Abstract

A 24-year-old man infected with human immunodeficiency virus type I rapidly progressed to acquired immune deficiency syndrome. His clinical picture was compatible with a presumptive diagnosis of cerebral toxoplasmosis. Application of a nested polymerase chain reaction (PCR) succeeded in detecting Toxoplasma gondii DNA in both the venous blood and cerebrospinal fluid specimens. This result indicates that PCR is a convenient tool for making a rapid and accurate diagnosis of cerebral toxoplasmosis, especially in developing countries.

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