Diagnosis of coronary artery disease in patients with atrial fibrillation using low tube voltage coronary CT angiography with isotonic low-concentration contrast agent

The International Journal of Cardiovascular Imaging
Yuning PanShizhong Bu

Abstract

This prospective study evaluated the image quality and accuracy of coronary computed tomography angiography (CCTA) for diagnosing coronary artery disease (CAD) in patients with atrial fibrillation (AF), in which CCTA used adaptive iterative dose reduction (AIDR) with a low tube voltage and low concentration of isotonic contrast agent. Sixty-eight consecutive patients with AF and suspected CAD were equally and randomly apportioned to two groups and underwent CCTA. In the experimental group, the contrast agent was iodixanol (270 mg I/mL), patients were scanned with 100 kV, and reconstruction was by AIDR. In the conventional scanning (control) group, the contrast agent was iopromide (370 mg I/mL), patients were scanned with 120 kV, and reconstruction was by filtered back projection. The image quality, effective radiation dose (E), and total iodine intake of the groups were compared. Thirty-nine patients with coronary artery stenosis later were given invasive coronary angiography (ICA). The groups were similar with regard to mean CT value, noise, and signal-to-noise and contrast-to-noise ratios. The figure of merit of the experimental group was significantly higher than that of the control group, while the E and total iodine were s...Continue Reading

References

Apr 4, 2002·Radiology·Thomas L Slovis
Mar 28, 2008·The International Journal of Cardiovascular Imaging·Frank J RybickiMarcelo F Di Carli
Feb 28, 2009·International Journal of Cardiology·Ilias TsiflikasChristof Burgstahler
Aug 22, 2009·AJR. American Journal of Roentgenology·Amy K HaraWilliam Pavlicek
Nov 26, 2009·AJR. American Journal of Roentgenology·Sundeep S PasrichaJohn M Troupis

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Citations

Apr 14, 2020·The International Journal of Cardiovascular Imaging·Johan H C ReiberJoachim Lotz

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