Diagnosis of exercise-induced bronchoconstriction: eucapnic voluntary hyperpnoea challenges identify previously undiagnosed elite athletes with exercise-induced bronchoconstriction

British Journal of Sports Medicine
J DickinsonGreg Whyte

Abstract

There is increasing evidence to suggest many elite athletes fail to recognise and report symptoms of exercise-induced bronchoconstriction (EIB), supporting the contention that athletes should be screened routinely for EIB. To screen elite British athletes for EIB using eucapnic voluntary hyperpnoea (EVH). 228 elite athletes provided written informed consent and completed an EVH challenge with maximal flow volume loops measured at baseline and 3, 5, 10 and 15 min following EVH. A fall of 10% in forced expiratory volume in 1 s (FEV(1)) from baseline was deemed positive. Two-way analysis of variance was conducted to compare FEV(1) at baseline and maximal change following EVH between EVH-positive and EVH-negative athletes who did and did not report a previous diagnosis of EIB. Significance was assumed if p ≤0.05. Following the EVH challenge 78 athletes (34%) demonstrated EVH positive. 57 out of the 78 (73%) athletes who demonstrated EVH positive did not have a previous diagnosis of EIB. 30 athletes reported a previous diagnosis of asthma, nine (30%) of whom demonstrated EVH negative. There was no significant difference between the magnitude of the fall in FEV(1) between athletes who reported a previous diagnosis of EIB and demonstr...Continue Reading

Citations

Sep 15, 2011·Current Allergy and Asthma Reports·Christopher Randolph
Aug 31, 2012·Clinical Medicine : Journal of the Royal College of Physicians of London·James H HullJonathan P Parsons
May 9, 2014·The Journal of Allergy and Clinical Immunology. in Practice·John M WeilerAmy Bronstone
Aug 21, 2015·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Oliver J PriceJames H Hull
Aug 31, 2013·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·J MolphyG Whyte
Feb 21, 2014·Expert Review of Respiratory Medicine·Oliver J PriceLes Ansley
Aug 26, 2015·Respiratory Medicine·N C WilliamsG R Sharpe
Jan 23, 2015·The Journal of Allergy and Clinical Immunology. in Practice·Oliver J PriceJames H Hull
May 25, 2016·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Enrico HefflerCaterina Bucca
Jul 28, 2016·Respirology : Official Journal of the Asian Pacific Society of Respirology·Irisz Karolina LevaiJohn W Dickinson
Apr 1, 2017·American Journal of Respiratory and Critical Care Medicine·Oliver J PriceJames H Hull
Feb 26, 2016·European Clinical Respiratory Journal·Sandra D Anderson
Apr 26, 2018·ERJ Open Research·Anna R JacksonJohn W Dickinson
Dec 21, 2018·International Journal of Sports Physiology and Performance·John MolphyGregory Whyte
Mar 27, 2019·Medicine and Science in Sports and Exercise·Andrew J SimpsonPascale Kippelen
Feb 25, 2015·Medicine and Science in Sports and Exercise·Andrew J SimpsonPascale Kippelen
Sep 12, 2020·Sports Medicine·Rikhard Mäki-HeikkiläLauri Lehtimäki
Jun 4, 2020·Clinical Physiology and Functional Imaging·Janne BurmanTuomas Jartti
Feb 28, 2013·Primary Care Respiratory Journal : Journal of the General Practice Airways Group·Les AnsleyJames H Hull
Aug 16, 2018·NPJ Primary Care Respiratory Medicine·Bhumika AggarwalNorbert Berend
Jul 6, 2019·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Andrew RoweBernard Donne
Oct 9, 2020·International Journal of Environmental Research and Public Health·Daniel Enrique Rodriguez Bauza, Patricia Silveyra
Dec 3, 2020·British Journal of Sports Medicine·Gareth N SandfordMichael Stephen Koehle
Aug 28, 2021·Scandinavian Journal of Medicine & Science in Sports·Rikhard Mäki-HeikkiläLauri Lehtimäki

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.